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Gene Review

IPT8  -  adenylate isopentenyltransferase 8

Arabidopsis thaliana

Synonyms: ATIPT8, ATP/ADP isopentenyltransferases, MVI11.16, PGA22, isopentenyltransferase 8
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High impact information on ATIPT8

  • A gain-of-function mutation in the PGA22 locus resulted in typical cytokinin responses [1].
  • Plants of the pga22 mutant accumulated at remarkably higher levels of isopentenyladenosine-5'-monophosphate and isopentenyladenosine when analyzed by mass spectrometry, suggesting that AtIPT8/PGA22 is a functional IPT that may direct the biosynthesis of cytokinins in planta via an isopentenyladenosine-5'-monophosphate-dependent pathway [1].


  1. The Arabidopsis AtIPT8/PGA22 gene encodes an isopentenyl transferase that is involved in de novo cytokinin biosynthesis. Sun, J., Niu, Q.W., Tarkowski, P., Zheng, B., Tarkowska, D., Sandberg, G., Chua, N.H., Zuo, J. Plant Physiol. (2003) [Pubmed]
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