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Gene Review

SHD  -  HSP90-like protein GRP94

Arabidopsis thaliana

Synonyms: AtHsp90-7, AtHsp90.7, HEAT SHOCK PROTEIN 90-7, HEAT SHOCK PROTEIN 90.7, HSP90.7, ...
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High impact information on SHD

  • Moreover, the effects of CLV3 overexpression that result in the elimination of SAM activity were abolished in the shd mutant, indicating that CLV function is dependent on SHD function [1].
  • Since the shd phenotypes in SAM and FM are similar to those of the clavata (clv) mutants, we have explored the possibility that CLV complex members could be SHD targets [1].
  • Overexpression of the SHD in transgenic plants causes a dominant negative phenotype [2].


  1. SHEPHERD is the Arabidopsis GRP94 responsible for the formation of functional CLAVATA proteins. Ishiguro, S., Watanabe, Y., Ito, N., Nonaka, H., Takeda, N., Sakai, T., Kanaya, H., Okada, K. EMBO J. (2002) [Pubmed]
  2. IRREGULAR TRICHOME BRANCH1 in Arabidopsis encodes a plant homolog of the actin-related protein2/3 complex activator Scar/WAVE that regulates actin and microtubule organization. Zhang, X., Dyachok, J., Krishnakumar, S., Smith, L.G., Oppenheimer, D.G. Plant Cell (2005) [Pubmed]
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