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Gene Review

PSAT  -  phosphoserine aminotransferase

Arabidopsis thaliana

Synonyms: PHOSPHOSERINE AMINOTRANSFERASE
 
 
 
 
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Disease relevance of PSAT

 

High impact information on PSAT

  • The AtPSAT is the only intracellular enzyme found so far that catalyzes an acyl-CoA-independent sterol ester formation [1].
 

Other interactions of PSAT

  • Two T-DNA insertion mutants in the AtPSAT gene, with strongly reduced (but still measurable) levels of sterol esters in their tissues, had no detectable PSAT activity in the microsomal fractions, suggesting that Arabidopsis possess other enzyme(s) capable of acylating sterols [1].

References

  1. Cellular sterol ester synthesis in plants is performed by an enzyme (phospholipid:sterol acyltransferase) different from the yeast and mammalian acyl-CoA:sterol acyltransferases. Banas, A., Carlsson, A.S., Huang, B., Lenman, M., Banas, W., Lee, M., Noiriel, A., Benveniste, P., Schaller, H., Bouvier-Navé, P., Stymne, S. J. Biol. Chem. (2005) [Pubmed]
 
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