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Gene Review:

CAPZA2 - capping protein (actin filament) muscle Z...

Homo sapiens

Synonyms: CAPPA2, CAPZ, CapZ alpha-2, F-actin-capping protein subunit alpha-2

Mueller, H.W. et al., Barron-Casella, E.A. et al.

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High impact information on CAPZA2

The human alpha 2 gene (CAPZA2) has been mapped to chromosome 7 position q31.2-q31.3 and the beta gene (CAPZB) to chromosome 1 region p36.1 [1].
Two newly identified exons and the CAPZA2 exons were amplified in tumor TX3095, which retains an amplified MET gene [2].

Biological context of CAPZA2

The new exons were localized close to MET and CAPZA2 [2].

References

Sequence analysis and chromosomal localization of human Cap Z. Conserved residues within the actin-binding domain may link Cap Z to gelsolin/severin and profilin protein families. Barron-Casella, E.A., Torres, M.A., Scherer, S.W., Heng, H.H., Tsui, L.C., Casella, J.F. J. Biol. Chem. (1995) [Pubmed]
Identification of an amplified gene cluster in glioma including two novel amplified genes isolated by exon trapping. Mueller, H.W., Michel, A., Heckel, D., Fischer, U., Tönnes, M., Tsui, L.C., Scherer, S., Zang, K.D., Meese, E. Hum. Genet. (1997) [Pubmed]

Contributions to this collaborative article are from individual authors of WikiGenes or mined by the WikiGenes Data Mining Engine from MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.About WikiGenes Open Access Licence Privacy Policy Terms of Use apsburg

AGOS_ABR007C	Ashbya gossypii ATCC 10895
CAPZA2	Bos taurus
CAPZA2	Canis lupus familiaris
CAPZA2	Gallus gallus
KLLA0B13453g	Kluyveromyces lactis NRRL Y-1140
CAPZA2	Macaca mulatta
MGG_12818	Magnaporthe oryzae 70-15
Capza2	Mus musculus
NCU03911	Neurospora crassa OR74A
CAPZA2	Pan troglodytes
Capza2	Rattus norvegicus
CAP1	Saccharomyces cerevisiae S288c
capza2	Xenopus (Silurana) tropicalis

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