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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

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Gene Review: 

ATG10  -  autophagy related 10

Homo sapiens

Synonyms: APG10, APG10-like, APG10L, Autophagy-related protein 10, DKFZP586I0418, ...
 
 
 
 
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High impact information on ATG10

  • We further show that two hydrophobic residues within the ubiquitin-fold region are important for autophagy: mutation at Y149 affects conjugate formation catalyzed by Atg10, an E2-like enzyme, while mutation at F154 has no effect on Atg12-Atg5 conjugate formation but its hydrophobic nature is essential for autophagy [1].

References

  1. Structure-Function Relationship of Atg12, a Ubiquitin-like Modifier Essential for Autophagy. Hanada, T., Ohsumi, Y. Autophagy. (2005) [Pubmed]
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