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Gene Review:

ARMC10 - armadillo repeat containing 10

Homo sapiens

Synonyms: Armadillo repeat-containing protein 10, MGC3195, PNAS-112, PNAS112, PSEC0198, ...

Huang, R. et al., Curtiss, N.P. et al.

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Disease relevance of ARMC10

A specific splicing variant of SVH, a novel human armadillo repeat protein, is up-regulated in hepatocellular carcinomas [1].

High impact information on ARMC10

Four variants of SVH, SVH-A, -B, -C, and -D, resulting from alternative splicing in the coding region of the SVH transcript, were observed and were all localized in endoplasmic reticulum (ER) [1].
We have extensively characterized the FBXL13, NAPE-PLD, and SVH genes as candidate myeloid tumor suppressors [2].

Analytical, diagnostic and therapeutic context of ARMC10

Northern blot revealed that SVH was expressed in most human adult tissues [1].

References

A specific splicing variant of SVH, a novel human armadillo repeat protein, is up-regulated in hepatocellular carcinomas. Huang, R., Xing, Z., Luan, Z., Wu, T., Wu, X., Hu, G. Cancer Res. (2003) [Pubmed]
Isolation and analysis of candidate myeloid tumor suppressor genes from a commonly deleted segment of 7q22. Curtiss, N.P., Bonifas, J.M., Lauchle, J.O., Balkman, J.D., Kratz, C.P., Emerling, B.M., Green, E.D., Le Beau, M.M., Shannon, K.M. Genomics (2005) [Pubmed]

Contributions to this collaborative article are from individual authors of WikiGenes or mined by the WikiGenes Data Mining Engine from MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.About WikiGenes Open Access Licence Privacy Policy Terms of Use apsburg

ARMC10	Bos taurus
ARMC10	Canis lupus familiaris
armc10	Danio rerio
ARMC10	Gallus gallus
LOC695210	Macaca mulatta
Armc10	Mus musculus
ARMC10	Pan troglodytes
Armc10	Rattus norvegicus
armc10	Xenopus (Silurana) tropicalis

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