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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

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Gene Review: 

FAR1  -  fatty acyl CoA reductase 1

Homo sapiens

Synonyms: FLJ22728, Fatty acyl-CoA reductase 1, MLSTD2, Male sterility domain-containing protein 2, PFCRD, ...
 
 
 
 
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High impact information on MLSTD2

  • Fatty acyl-CoA esters were the substrate of FAR1, and the enzyme required NADPH as a cofactor [1].
  • Confocal light microscopy indicated that FAR1 and FAR2 were localized in the peroxisome [1].
  • The FAR1 mRNA was detected in many mouse tissues with the highest level found in the preputial gland, a modified sebaceous gland [1].

References

  1. Mammalian wax biosynthesis. I. Identification of two fatty acyl-Coenzyme A reductases with different substrate specificities and tissue distributions. Cheng, J.B., Russell, D.W. J. Biol. Chem. (2004) [Pubmed]
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