Gene Review:
DECR1 - 2,4-dienoyl CoA reductase 1, mitochondrial
Homo sapiens
Synonyms:
2,4-dienoyl-CoA reductase, mitochondrial, DECR, NADPH, SDR18C1, Short chain dehydrogenase/reductase family 18C member 1
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- Quantitative evolutionary design of glucose 6-phosphate dehydrogenase expression in human erythrocytes. Salvador, A., Savageau, M.A. Proc. Natl. Acad. Sci. U.S.A. (2003)
- Compartmental loss of NADPH diaphorase in the neuropil of the human striatum in Huntington's disease. Morton, A.J., Nicholson, L.F., Faull, R.L. Neuroscience (1993)
- NADPH diaphorase histochemistry of the human hypothalamus. Sangruchi, T., Kowall, N.W. Neuroscience (1991)
- Hydroxymethylvinyl ketone: a reactive Michael acceptor formed by the oxidation of 3-butene-1,2-diol by cDNA-expressed human cytochrome P450s and mouse, rat, and human liver microsomes. Krause, R.J., Kemper, R.A., Elfarra, A.A. Chem. Res. Toxicol. (2001)
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- Mutations in the genes encoding 11beta-hydroxysteroid dehydrogenase type 1 and hexose-6-phosphate dehydrogenase interact to cause cortisone reductase deficiency. Draper, N., Walker, E.A., Bujalska, I.J., Tomlinson, J.W., Chalder, S.M., Arlt, W., Lavery, G.G., Bedendo, O., Ray, D.W., Laing, I., Malunowicz, E., White, P.C., Hewison, M., Mason, P.J., Connell, J.M., Shackleton, C.H., Stewart, P.M. Nat. Genet. (2003)
- Pyridine nucleotide-dependent superoxide production by a cell-free system from human granulocytes. Babior, B.M., Curnutte, J.T., Kipnes, B.S. J. Clin. Invest. (1975)
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- PTR1: a reductase mediating salvage of oxidized pteridines and methotrexate resistance in the protozoan parasite Leishmania major. Bello, A.R., Nare, B., Freedman, D., Hardy, L., Beverley, S.M. Proc. Natl. Acad. Sci. U.S.A. (1994)
- Genetic susceptibility to benzene-induced toxicity: role of NADPH: quinone oxidoreductase-1. Bauer, A.K., Faiola, B., Abernethy, D.J., Marchan, R., Pluta, L.J., Wong, V.A., Roberts, K., Jaiswal, A.K., Gonzalez, F.J., Butterworth, B.E., Borghoff, S., Parkinson, H., Everitt, J., Recio, L. Cancer Res. (2003)
- Co-induction of fatty acid reductase and luciferase during development of bacterial bioluminescence. Riendeau, D., Meighen, E. J. Biol. Chem. (1980)
- Atomic structure of ferredoxin-NADP+ reductase: prototype for a structurally novel flavoenzyme family. Karplus, P.A., Daniels, M.J., Herriott, J.R. Science (1991)
- Arachidonic acid and other fatty acids directly activate potassium channels in smooth muscle cells. Ordway, R.W., Walsh, J.V., Singer, J.J. Science (1989)
- Reductase activity encoded by the HM1 disease resistance gene in maize. Johal, G.S., Briggs, S.P. Science (1992)
- A mammalian H+ channel generated through alternative splicing of the NADPH oxidase homolog NOH-1. Bánfi, B., Maturana, A., Jaconi, S., Arnaudeau, S., Laforge, T., Sinha, B., Ligeti, E., Demaurex, N., Krause, K.H. Science (2000)
- NADPH-binding component of the respiratory burst oxidase system: studies using neutrophil membranes from patients with chronic granulomatous disease lacking the beta-subunit of cytochrome b558. Tsunawaki, S., Mizunari, H., Namiki, H., Kuratsuji, T. J. Exp. Med. (1994)
- NADPH-dependent beta-oxidation of unsaturated fatty acids with double bonds extending from odd-numbered carbon atoms. Smeland, T.E., Nada, M., Cuebas, D., Schulz, H. Proc. Natl. Acad. Sci. U.S.A. (1992)
- Nitric oxide mediates network oscillations of olfactory interneurons in a terrestrial mollusc. Gelperin, A. Nature (1994)
- Priming of neutrophils for enhanced release of oxygen metabolites by bacterial lipopolysaccharide. Evidence for increased activity of the superoxide-producing enzyme. Guthrie, L.A., McPhail, L.C., Henson, P.M., Johnston, R.B. J. Exp. Med. (1984)
- The mechanism of dienoyl-CoA reduction by 2,4-dienoyl-CoA reductase is stepwise: observation of a dienolate intermediate. Fillgrove, K.L., Anderson, V.E. Biochemistry (2001)
- Electron currents generated by the human phagocyte NADPH oxidase. Schrenzel, J., Serrander, L., Bánfi, B., Nüsse, O., Fouyouzi, R., Lew, D.P., Demaurex, N., Krause, K.H. Nature (1998)
- Novel NADPH-binding domain revealed by the crystal structure of aldose reductase. Rondeau, J.M., Tête-Favier, F., Podjarny, A., Reymann, J.M., Barth, P., Biellmann, J.F., Moras, D. Nature (1992)
- 11 beta-Hydroxysteroid dehydrogenase and the syndrome of apparent mineralocorticoid excess. White, P.C., Mune, T., Agarwal, A.K. Endocr. Rev. (1997)
- Unexpected genetic and structural relationships of a long-forgotten flavoenzyme to NAD(P)H:quinone reductase (DT-diaphorase). Zhao, Q., Yang, X.L., Holtzclaw, W.D., Talalay, P. Proc. Natl. Acad. Sci. U.S.A. (1997)
- Catalase and glutathione peroxidase are equally active in detoxification of hydrogen peroxide in human erythrocytes. Gaetani, G.F., Galiano, S., Canepa, L., Ferraris, A.M., Kirkman, H.N. Blood (1989)
- Identification of amino acids required for the functional up-regulation of human dihydrofolate reductase protein in response to antifolate Treatment. Skacel, N., Menon, L.G., Mishra, P.J., Peters, R., Banerjee, D., Bertino, J.R., Abali, E.E. J. Biol. Chem. (2005)
- Interaction of endothelial and neuronal nitric-oxide synthases with the bradykinin B2 receptor. Binding of an inhibitory peptide to the oxygenase domain blocks uncoupled NADPH oxidation. Golser, R., Gorren, A.C., Leber, A., Andrew, P., Habisch, H.J., Werner, E.R., Schmidt, K., Venema, R.C., Mayer, B. J. Biol. Chem. (2000)
- Differences in the inhibition of cytochromes P450 3A4 and 3A5 by metabolite-inhibitor complex-forming drugs. McConn, D.J., Lin, Y.S., Allen, K., Kunze, K.L., Thummel, K.E. Drug Metab. Dispos. (2004)
- Multiple steps determine the overall rate of the reduction of 5alpha-dihydrotestosterone catalyzed by human type 3 3alpha-hydroxysteroid dehydrogenase: implications for the elimination of androgens. Jin, Y., Penning, T.M. Biochemistry (2006)
- Crystal structure of human prostaglandin F synthase (AKR1C3). Komoto, J., Yamada, T., Watanabe, K., Takusagawa, F. Biochemistry (2004)
- Investigation of the major human hepatic cytochrome P450 involved in 4-hydroxylation and N-dechloroethylation of trofosfamide. May-Manke, A., Kroemer, H., Hempel, G., Bohnenstengel, F., Hohenlöchter, B., Blaschke, G., Boos, J. Cancer Chemother. Pharmacol. (1999)
- Characterization of mitochondrial thioredoxin reductase from C. elegans. Lacey, B.M., Hondal, R.J. Biochem. Biophys. Res. Commun. (2006)
- Immunohistochemical localization of endothelial nitric oxide synthase in human testis, epididymis, and vas deferens suggests a possible role for nitric oxide in spermatogenesis, sperm maturation, and programmed cell death. Zini, A., O'Bryan, M.K., Magid, M.S., Schlegel, P.N. Biol. Reprod. (1996)
- ZNF143 mediates basal and tissue-specific expression of human transaldolase. Grossman, C.E., Qian, Y., Banki, K., Perl, A. J. Biol. Chem. (2004)
- Mechanism of Ca2+ activation of the NADPH oxidase 5 (NOX5). Bánfi, B., Tirone, F., Durussel, I., Knisz, J., Moskwa, P., Molnár, G.Z., Krause, K.H., Cox, J.A. J. Biol. Chem. (2004)
- Role of CYP3A4 in human hepatic diltiazem N-demethylation: inhibition of CYP3A4 activity by oxidized diltiazem metabolites. Sutton, D., Butler, A.M., Nadin, L., Murray, M. J. Pharmacol. Exp. Ther. (1997)
- Inhibition of coumarin 7-hydroxylase activity in human liver microsomes. Draper, A.J., Madan, A., Parkinson, A. Arch. Biochem. Biophys. (1997)
- In vitro oxidation of oxicam NSAIDS by a human liver cytochrome P450. Zhao, J., Leemann, T., Dayer, P. Life Sci. (1992)
- Engineering of a functional human NADH-dependent cytochrome P450 system. Döhr, O., Paine, M.J., Friedberg, T., Roberts, G.C., Wolf, C.R. Proc. Natl. Acad. Sci. U.S.A. (2001)
- Human methionine synthase reductase is a molecular chaperone for human methionine synthase. Yamada, K., Gravel, R.A., Toraya, T., Matthews, R.G. Proc. Natl. Acad. Sci. U.S.A. (2006)
- CYP2D6 catalyzes tamoxifen 4-hydroxylation in human liver. Dehal, S.S., Kupfer, D. Cancer Res. (1997)
- Modulation of ion channels in rod photoreceptors by nitric oxide. Kurenny, D.E., Moroz, L.L., Turner, R.W., Sharkey, K.A., Barnes, S. Neuron (1994)
- Reductive metabolism of carbon tetrachloride by human cytochromes P-450 reconstituted in phospholipid vesicles: mass spectral identification of trichloromethyl radical bound to dioleoyl phosphatidylcholine. Trudell, J.R., Bösterling, B., Trevor, A.J. Proc. Natl. Acad. Sci. U.S.A. (1982)
- Ferryl intermediates of catalase captured by time-resolved Weissenberg crystallography and UV-VIS spectroscopy. Gouet, P., Jouve, H.M., Williams, P.A., Andersson, I., Andreoletti, P., Nussaume, L., Hajdu, J. Nat. Struct. Biol. (1996)
- Enhanced dihydroflavonol-4-reductase activity and NAD homeostasis leading to cell death tolerance in transgenic rice. Hayashi, M., Takahashi, H., Tamura, K., Huang, J., Yu, L.H., Kawai-Yamada, M., Tezuka, T., Uchimiya, H. Proc. Natl. Acad. Sci. U.S.A. (2005)
- Dissection of NADPH-cytochrome P450 oxidoreductase into distinct functional domains. Smith, G.C., Tew, D.G., Wolf, C.R. Proc. Natl. Acad. Sci. U.S.A. (1994)