The world's first wiki where authorship really matters (Nature Genetics, 2008). Due credit and reputation for authors. Imagine a global collaborative knowledge base for original thoughts. Search thousands of articles and collaborate with scientists around the globe.

wikigene or wiki gene protein drug chemical gene disease author authorship tracking collaborative publishing evolutionary knowledge reputation system wiki2.0 global collaboration genes proteins drugs chemicals diseases compound
Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)



Gene Review

RPL15A  -  ribosomal 60S subunit protein L15A

Saccharomyces cerevisiae S288c

Synonyms: 60S ribosomal protein L15-A, L13, RP15R, RPL10A, RPL13A, ...
Welcome! If you are familiar with the subject of this article, you can contribute to this open access knowledge base by deleting incorrect information, restructuring or completely rewriting any text. Read more.

Disease relevance of RPL15A


High impact information on RPL15A

  • We show here that an L13 mutant extract cannot form stable base-pairing at room temperature but is permissive for U1-5'ss base-pairing at low temperature [2].
  • The L13 phenotype has therefore been interpreted to indicate that WT U1C contributes to 5'ss-U1 snRNA stabilization by binding to the RNA duplex [2].


  1. Disruption of the MRP-L23 gene encoding the mitochondrial ribosomal protein L23 is lethal for Kluyveromyces lactis but not for Saccharomyces cerevisiae. Murray, G.L., Bao, W.G., Fukuhara, H., Zuo, X.M., Clark-Walker, G.D., Chen, X.J. Curr. Genet. (2000) [Pubmed]
  2. Effects of the U1C L13 mutation and temperature regulation of yeast commitment complex formation. Du, H., Tardiff, D.F., Moore, M.J., Rosbash, M. Proc. Natl. Acad. Sci. U.S.A. (2004) [Pubmed]
WikiGenes - Universities