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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

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Gene Review: 

POP5  -  Pop5p

Saccharomyces cerevisiae S288c

Synonyms: FUN53, RNA-processing protein POP5, RNases P/MRP 19.6 kDa subunit, Ribonucleases P/MRP protein subunit POP5, YAL033W
 
 
 
 
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High impact information on POP5

  • DNA sequence analysis of these mutant alleles and of the corresponding wild-type region revealed that each mutation was a single substitution not in the previously identified gene FUN19, but in the adjacent, newly identified essential gene FUN53 [1].
  • However, the results obtained with FUN53 suggest that there may also be significant constraints on mutagenesis in yeast [1].

References

  1. Molecular analysis of Saccharomyces cerevisiae chromosome I. On the number of genes and the identification of essential genes using temperature-sensitive-lethal mutations. Harris, S.D., Cheng, J., Pugh, T.A., Pringle, J.R. J. Mol. Biol. (1992) [Pubmed]
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