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Gene Review

NUP60  -  Nup60p

Saccharomyces cerevisiae S288c

Synonyms: FUN17, Nuclear pore protein NUP60, Nucleoporin NUP60, YAR002W
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High impact information on NUP60


Other interactions of NUP60

  • Yeast lacking Nup60p also fail to anchor Nup2p at the NPC, resulting in the mislocalization of Nup2p to the nucleoplasm and cytoplasm [3].


  1. Mlp-dependent anchorage and stabilization of a desumoylating enzyme is required to prevent clonal lethality. Zhao, X., Wu, C.Y., Blobel, G. J. Cell Biol. (2004) [Pubmed]
  2. Nup2p dynamically associates with the distal regions of the yeast nuclear pore complex. Dilworth, D.J., Suprapto, A., Padovan, J.C., Chait, B.T., Wozniak, R.W., Rout, M.P., Aitchison, J.D. J. Cell Biol. (2001) [Pubmed]
  3. The nucleoporin Nup60p functions as a Gsp1p-GTP-sensitive tether for Nup2p at the nuclear pore complex. Denning, D., Mykytka, B., Allen, N.P., Huang, L., Al Burlingame, n.u.l.l., Rexach, M. J. Cell Biol. (2001) [Pubmed]
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