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Gene Review:

COX9 - cytochrome c oxidase subunit VIIa

Saccharomyces cerevisiae S288c

Synonyms: Cytochrome c oxidase polypeptide VIIA, Cytochrome c oxidase subunit 7A, D2520, YDL067C

Wright, R.M. et al., McEwen, J.E. et al.

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High impact information on COX9

One class contains three complementation groups whose strains carry mutations in the COX4, COX5a, or COX9 genes [1].
From the nucleotide sequence of COX9, we deduce that subunit VIIa is derived from a precursor that is 59 amino acids in length (Mr = 6963) [2].
COX9 exists as a single copy in the haploid genome of S. cerevisiae and produces one major transcript [2].
Characterization of COX9, the nuclear gene encoding the yeast mitochondrial protein cytochrome c oxidase subunit VIIa. Subunit VIIa lacks a leader peptide and is an essential component of the holoenzyme [2].

References

Nuclear functions required for cytochrome c oxidase biogenesis in Saccharomyces cerevisiae. Characterization of mutants in 34 complementation groups. McEwen, J.E., Ko, C., Kloeckner-Gruissem, B., Poyton, R.O. J. Biol. Chem. (1986) [Pubmed]
Characterization of COX9, the nuclear gene encoding the yeast mitochondrial protein cytochrome c oxidase subunit VIIa. Subunit VIIa lacks a leader peptide and is an essential component of the holoenzyme. Wright, R.M., Dircks, L.K., Poyton, R.O. J. Biol. Chem. (1986) [Pubmed]

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