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Gene Review

SEC26  -  Sec26p

Saccharomyces cerevisiae S288c

Synonyms: Beta-COP, Beta-coat protein, Coatomer subunit beta, YD8419.05C, YDR238C
 
 
 
 
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High impact information on SEC26

  • To understand better the role of non-clathrin coat proteins in membrane traffic, we have cloned and characterized two essential genes encoding subunits of the yeast coatomer, SEC26 and SEC27 [1].
  • Sec26p-depleted cells accumulate endoplasmic reticulum (ER) forms of secretory precursor proteins, and growth ceases after a dramatic accumulation of ER membranes [1].

References

  1. Yeast beta- and beta'-coat proteins (COP). Two coatomer subunits essential for endoplasmic reticulum-to-Golgi protein traffic. Duden, R., Hosobuchi, M., Hamamoto, S., Winey, M., Byers, B., Schekman, R. J. Biol. Chem. (1994) [Pubmed]
 
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