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Gene Review

Pola1  -  polymerase (DNA directed), alpha 1,...

Rattus norvegicus

Synonyms: DNA polymerase alpha catalytic subunit, DNA polymerase alpha catalytic subunit p180, Pola
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High impact information on Pola1

  • System A transport activity shows a dependence on pH, and recent results suggest the presence of critical histidine residues on the A carrier that may be responsible for its pH dependence (Bertran, J., Roca, A., Pola, E., Testar, X., Zorzano, A. & Palacín, M. (1991) J. Biol. Chem. 266, 798-802) [1].


  1. Vanadate stimulates system A amino acid transport activity in skeletal muscle. Evidence for the involvement of intracellular pH as a mediator of vanadate action. Muñoz, P., Gumà, A., Camps, M., Furriols, M., Testar, X., Palacín, M., Zorzano, A. J. Biol. Chem. (1992) [Pubmed]
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