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Gene Review:

KEL2 - Kel2p

Saccharomyces cerevisiae S288c

Synonyms: G8585, Kelch repeat-containing protein 2, YGR238C

Knaus, M. et al., Philips, J. et al.

Philips, Herskowitz,

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High impact information on KEL2

The localization to bud and shmoo tips requires an intact actin cytoskeleton and the kelch-domain-containing proteins Kel1p and Kel2p [1].
KEL2, which corresponds to ORF YGR238c, encodes a protein highly similar to Kel1p [2].

Biological context of KEL2

Both Kel1p and Kel2p localized to the site where cell fusion occurs during mating and to regions of polarized growth during vegetative growth [2].

References

The Bud14p-Glc7p complex functions as a cortical regulator of dynein in budding yeast. Knaus, M., Cameroni, E., Pedruzzi, I., Tatchell, K., De Virgilio, C., Peter, M. EMBO J. (2005) [Pubmed]
Identification of Kel1p, a kelch domain-containing protein involved in cell fusion and morphology in Saccharomyces cerevisiae. Philips, J., Herskowitz, I. J. Cell Biol. (1998) [Pubmed]

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