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Gene Review

DDR2  -  Ddr2p

Saccharomyces cerevisiae S288c

Synonyms: Protein DDR2, YOL052BC, YOL052C-A, YOL053C-A
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High impact information on DDR2

  • The stress-responsive DDR2 gene (previously called DDRA2) of Saccharomyces cerevisiae is transcribed at elevated levels following stress caused by heat shock or DNA damage [1].
  • The DDR2 gene encodes a small hydrophobic 61 amino acid polypeptide located on chromosome XV adjacent to the SPE2 locus [2].


  1. Identification of cis and trans components of a novel heat shock stress regulatory pathway in Saccharomyces cerevisiae. Kobayashi, N., McEntee, K. Mol. Cell. Biol. (1993) [Pubmed]
  2. Structure and functional analysis of the multistress response gene DDR2 from Saccharomyces cerevisiae. Kobayashi, N., McClanahan, T.K., Simon, J.R., Treger, J.M., McEntee, K. Biochem. Biophys. Res. Commun. (1996) [Pubmed]
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