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Gene Review

EFT1  -  elongation factor 2

Saccharomyces cerevisiae S288c

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High impact information on EFT1

  • Although EFT1 and EFT2 are located on separate chromosomes, the DNA sequences of the two genes differ at only four positions out of 2526 base pairs, and the predicted protein sequences are identical [1].
  • In contrast, the sequences essential for the transcription of EFT1 were localized to the region between the start ATG and the stop codon of the VPS17 gene that terminates 267 nt upstream on the same strand [2].


  1. Saccharomyces cerevisiae elongation factor 2. Genetic cloning, characterization of expression, and G-domain modeling. Perentesis, J.P., Phan, L.D., Gleason, W.B., LaPorte, D.C., Livingston, D.M., Bodley, J.W. J. Biol. Chem. (1992) [Pubmed]
  2. Differential transcription of the two Saccharomyces cerevisiae genes encoding elongation factor 2. Veldman, S., Rao, S., Bodley, J.W. Gene (1994) [Pubmed]
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