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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

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Gene Review: 

EFT2  -  elongation factor 2

Saccharomyces cerevisiae S288c

 
 
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High impact information on EFT2

  • Although EFT1 and EFT2 are located on separate chromosomes, the DNA sequences of the two genes differ at only four positions out of 2526 base pairs, and the predicted protein sequences are identical [1].
  • Using TAP tagging, Kti11p contacts Elongator and translational proteins (Rps7Ap, Rps19Ap Eft2p, Yil103wp, Dph2p) [2].

References

  1. Saccharomyces cerevisiae elongation factor 2. Genetic cloning, characterization of expression, and G-domain modeling. Perentesis, J.P., Phan, L.D., Gleason, W.B., LaPorte, D.C., Livingston, D.M., Bodley, J.W. J. Biol. Chem. (1992) [Pubmed]
  2. Elongator's toxin-target (TOT) function is nuclear localization sequence dependent and suppressed by post-translational modification. Fichtner, L., Jablonowski, D., Schierhorn, A., Kitamoto, H.K., Stark, M.J., Schaffrath, R. Mol. Microbiol. (2003) [Pubmed]
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