Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)

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Gene Review:

EPS1 - protein disulfide isomerase EPS1

Saccharomyces cerevisiae S288c

Synonyms: ER-retained PMA1-suppressing protein 1, YIA5W, YIL005W

Wang, Q. et al., He, J. et al., Wang, Q. et al.

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High impact information on EPS1

Although Eps1 interaction with wild-type Pma1 was not detected, Eps1 co-immunoprecipitates with Pma1-D378N [1].
In the absence of Pma1-D378N, ER export of wild-type Pma1 is not affected by eps1 deletion, but export of the plasma membrane protein Gas1 is delayed [2].
Effect of EPS1 gene deletion in Saccharomyces cerevisiae on the secretion of foreign proteins which have disulfide bridges [3].

References

Substrate recognition in ER-associated degradation mediated by Eps1, a member of the protein disulfide isomerase family. Wang, Q., Chang, A. EMBO J. (2003) [Pubmed]
Eps1, a novel PDI-related protein involved in ER quality control in yeast. Wang, Q., Chang, A. EMBO J. (1999) [Pubmed]
Effect of EPS1 gene deletion in Saccharomyces cerevisiae on the secretion of foreign proteins which have disulfide bridges. He, J., Sakamoto, T., Song, Y., Saito, A., Harada, A., Azakami, H., Kato, A. FEBS Lett. (2005) [Pubmed]

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