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Gene Review

PML39  -  Pml39p

Saccharomyces cerevisiae S288c

Synonyms: 39 kDa pre-mRNA leakage protein, Pre-mRNA leakage protein 39, YM8339.12, YML107C
 
 
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High impact information on PML39

  • Moreover, pml39delta partially rescues the thermosensitive phenotypes of messenger ribonucleoparticles (mRNPs) assembly mutants, indicating that PML39 deletion also bypasses the requirement for normally assembled mRNPs [1].
  • Using a genetic screen, we have identified a previously uncharacterized Saccharomyces cerevisiae open reading frame (renamed PML39) that displays a specific interaction with nucleoporins of the Nup84 complex [1].

References

  1. Pml39, a novel protein of the nuclear periphery required for nuclear retention of improper messenger ribonucleoparticles. Palancade, B., Zuccolo, M., Loeillet, S., Nicolas, A., Doye, V. Mol. Biol. Cell (2005) [Pubmed]
 
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