The world's first wiki where authorship really matters (Nature Genetics, 2008). Due credit and reputation for authors. Imagine a global collaborative knowledge base for original thoughts. Search thousands of articles and collaborate with scientists around the globe.

wikigene or wiki gene protein drug chemical gene disease author authorship tracking collaborative publishing evolutionary knowledge reputation system wiki2.0 global collaboration genes proteins drugs chemicals diseases compound
Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

Editor

Share

Personal info

View

Links

  • Homologues
  • NCBI Gene
  • NCBI SNP
  • iHOP resource
  • SNPedia
  • UniProt

Table of contents

About

Terms

 

Gene Review: 

SSK2  -  Ssk2p

Saccharomyces cerevisiae S288c

Synonyms: MAP kinase kinase kinase SSK2, N3276, Suppressor of sensor kinase 2, YNR031C
 
 
Welcome! If you are familiar with the subject of this article, you can contribute to this open access knowledge base by deleting incorrect information, restructuring or completely rewriting any text. Read more.
 

High impact information on SSK2

  • Mcs4 acts upstream of Wak1, a homolog of the SSK2 and SSK22 MEK kinases, which transmits the stress signal to the Wis1 MEK [1].
  • The SSK1 C-terminal receiver domain interacts with an N-terminal segment of SSK2 [2].
  • A conserved threonine residue (Thr1460) in the activation loop of SSK2 is important for kinase activity [2].
 

Other interactions of SSK2

  • Activation of the yeast SSK2 MAP kinase kinase kinase by the SSK1 two-component response regulator [2].

References

  1. The Mcs4 response regulator coordinately controls the stress-activated Wak1-Wis1-Sty1 MAP kinase pathway and fission yeast cell cycle. Shieh, J.C., Wilkinson, M.G., Buck, V., Morgan, B.A., Makino, K., Millar, J.B. Genes Dev. (1997) [Pubmed]
  2. Activation of the yeast SSK2 MAP kinase kinase kinase by the SSK1 two-component response regulator. Posas, F., Saito, H. EMBO J. (1998) [Pubmed]
Contributions to this collaborative article are from individual authors of WikiGenes or mined by the WikiGenes Data Mining Engine from MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.About WikiGenesOpen Access LicencePrivacy PolicyTerms of Useapsburg
 
WikiGenes - Universities