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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

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Gene Review: 

SSK22  -  Ssk22p

Saccharomyces cerevisiae S288c

Synonyms: MAP kinase kinase kinase SSK22, Serine/threonine-protein kinase SSK22, Suppressor of sensor kinase 22, YCR073C, YCR73C
 
 
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High impact information on SSK22

  • The SLN1-YPD1-SSK1 two-component osmosensor activates the SSK2 and SSK22 MAPKKKs by direct interaction of the SSK1 response regulator with these MAPKKKs [1].
  • We cloned and characterized Neurospora NcSSK22 and NcPBS2 genes, similar to yeast SSK22 mitogen-activated protein (MAP) kinase kinase kinase and the PBS2 MAP kinase kinase genes, respectively [2].
 

Other interactions of SSK22

  • Putative homologs of SSK22 MAPKK kinase and PBS2 MAPK kinase of Saccharomyces cerevisiae encoded by os-4 and os-5 genes for osmotic sensitivity and fungicide resistance in Neurospora crassa [2].

References

  1. Requirement of STE50 for osmostress-induced activation of the STE11 mitogen-activated protein kinase kinase kinase in the high-osmolarity glycerol response pathway. Posas, F., Witten, E.A., Saito, H. Mol. Cell. Biol. (1998) [Pubmed]
  2. Putative homologs of SSK22 MAPKK kinase and PBS2 MAPK kinase of Saccharomyces cerevisiae encoded by os-4 and os-5 genes for osmotic sensitivity and fungicide resistance in Neurospora crassa. Fujimura, M., Ochiai, N., Oshima, M., Motoyama, T., Ichiishi, A., Usami, R., Horikoshi, K., Yamaguchi, I. Biosci. Biotechnol. Biochem. (2003) [Pubmed]
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