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Gene Review

DLD3  -  Dld3p

Saccharomyces cerevisiae S288c

Synonyms: D-LCR, D-lactate ferricytochrome C oxidoreductase, YEL071W
 
 
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High impact information on DLD3

  • For example, in yeast cells lacking the mitochondrial genome, the expression of several nuclear genes, such as CIT2 (citrate synthase), MRP13 (mitochondrial ribosomal protein), and DLD3 (d-lactate dehydrogenase) has been reported to be altered [1].
  • Sequence analysis reveals that the human and mouse transcripts encode novel proteins that display strong similarities to the yeast D-lactate dehydrogenase proteins DLD1, AIP2, and YEL071W [2].

References

  1. Interorganellar communication. Altered nuclear gene expression profiles in a yeast mitochondrial dna mutant. Traven, A., Wong, J.M., Xu, D., Sopta, M., Ingles, C.J. J. Biol. Chem. (2001) [Pubmed]
  2. Identification of putative mammalian D-lactate dehydrogenase enzymes. Flick, M.J., Konieczny, S.F. Biochem. Biophys. Res. Commun. (2002) [Pubmed]
 
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