Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)

Editor

Personal info

View

About

Terms

Javascript disabled

Please enable Javascript support in your browser to use this application.

Instructions on how to enable JavaScript on different browsers can be found here: http://www.google.com/support/bin/answer.py?answer=23852.

[edit this page]

Gene Review:

CLIC3 - chloride intracellular channel 3

Homo sapiens

Synonyms: Chloride intracellular channel protein 3

Qian, Z. et al.

Welcome! If you are familiar with the subject of this article, you can contribute to this open access knowledge base by deleting incorrect information, restructuring or completely rewriting any text. Read more.

High impact information on CLIC3

Taken together, these results suggest that CLIC3 is a new member of the human CLIC family [1].
The specific association of CLIC3 with the COOH-terminal tail of ERK7 suggests that CLIC3 may play a role in the regulation of cell growth [1].

Associations of CLIC3 with chemical compounds

Like NCC27/CLIC1, CLIC3 is predominantly localized in the nucleus and stimulates chloride conductance when expressed in cells [1].

Analytical, diagnostic and therapeutic context of CLIC3

The interaction between CLIC3 and ERK7 in mammalian cells was confirmed by co-immunoprecipitation [1].

References

Molecular cloning and characterization of a mitogen-activated protein kinase-associated intracellular chloride channel. Qian, Z., Okuhara, D., Abe, M.K., Rosner, M.R. J. Biol. Chem. (1999) [Pubmed]

Contributions to this collaborative article are from individual authors of WikiGenes or mined by the WikiGenes Data Mining Engine from MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.About WikiGenes Open Access Licence Privacy Policy Terms of Use apsburg

CLIC3	Bos taurus
CLIC3	Canis lupus familiaris
clica	Danio rerio
LOC417293	Gallus gallus
LOC721634	Macaca mulatta
Clic3	Mus musculus
CLIC3	Pan troglodytes
Clic3	Rattus norvegicus
clic3	Xenopus (Silurana) tropicalis

The world's first wiki where authorship really matters (Nature Genetics, 2008). Due credit and reputation for authors. Imagine a global collaborative knowledge base for original thoughts. Search thousands of articles and collaborate with scientists around the globe.