Gene Review:
CLIC1 - chloride intracellular channel 1
Homo sapiens
Synonyms:
Chloride channel ABP, Chloride intracellular channel protein 1, G6, NCC27, Nuclear chloride ion channel 27, ...
- AKAP350 at the Golgi apparatus. II. Association of AKAP350 with a novel chloride intracellular channel (CLIC) family member. Shanks, R.A., Larocca, M.C., Berryman, M., Edwards, J.C., Urushidani, T., Navarre, J., Goldenring, J.R. J. Biol. Chem. (2002)
- Overexpression of CLIC1 in human gastric carcinoma and its clinicopathological significance. Chen, C.D., Wang, C.S., Huang, Y.H., Chien, K.Y., Liang, Y., Chen, W.J., Lin, K.H. Proteomics (2007)
- Antisense suppression of the chloride intracellular channel family induces apoptosis, enhances tumor necrosis factor {alpha}-induced apoptosis, and inhibits tumor growth. Suh, K.S., Mutoh, M., Gerdes, M., Crutchley, J.M., Mutoh, T., Edwards, L.E., Dumont, R.A., Sodha, P., Cheng, C., Glick, A., Yuspa, S.H. Cancer Res. (2005)
- Genetic variability among serotype G6 human rotaviruses: identification of a novel lineage isolated in Hungary. Bányai, K., Gentsch, J.R., Griffin, D.D., Holmes, J.L., Glass, R.I., Szücs, G. J. Med. Virol. (2003)
- Glutathione transferases: new functions. Oakley, A.J. Curr. Opin. Struct. Biol. (2005)
- Functional characterization of the NCC27 nuclear protein in stable transfected CHO-K1 cells. Tonini, R., Ferroni, A., Valenzuela, S.M., Warton, K., Campbell, T.J., Breit, S.N., Mazzanti, M. FASEB J. (2000)
- Expression of proteins coincident with inducible radioprotection in human lung epithelial cells. Gamble, S.C., Dunn, M.J., Wheeler, C.H., Joiner, M.C., Adu-Poku, A., Arrand, J.E. Cancer Res. (2000)
- Identification of a novel member of the chloride intracellular channel gene family (CLIC5) that associates with the actin cytoskeleton of placental microvilli. Berryman, M., Bretscher, A. Mol. Biol. Cell (2000)
- Chloride intracellular channel protein CLIC4 (p64H1) binds directly to brain dynamin I in a complex containing actin, tubulin and 14-3-3 isoforms. Suginta, W., Karoulias, N., Aitken, A., Ashley, R.H. Biochem. J. (2001)
- The intracellular chloride ion channel protein CLIC1 undergoes a redox-controlled structural transition. Littler, D.R., Harrop, S.J., Fairlie, W.D., Brown, L.J., Pankhurst, G.J., Pankhurst, S., DeMaere, M.Z., Campbell, T.J., Bauskin, A.R., Tonini, R., Mazzanti, M., Breit, S.N., Curmi, P.M. J. Biol. Chem. (2004)
- Proteomic analysis on insulin signaling in human hematopoietic cells: identification of CLIC1 and SRp20 as novel downstream effectors of insulin. Saeki, K., Yasugi, E., Okuma, E., Breit, S.N., Nakamura, M., Toda, T., Kaburagi, Y., Yuo, A. Am. J. Physiol. Endocrinol. Metab. (2005)
- Involvement of the intracellular ion channel CLIC1 in microglia-mediated beta-amyloid-induced neurotoxicity. Novarino, G., Fabrizi, C., Tonini, R., Denti, M.A., Malchiodi-Albedi, F., Lauro, G.M., Sacchetti, B., Paradisi, S., Ferroni, A., Curmi, P.M., Breit, S.N., Mazzanti, M. J. Neurosci. (2004)
- Differential expression of a chloride intracellular channel gene, CLIC4, in transforming growth factor-beta1-mediated conversion of fibroblasts to myofibroblasts. Rønnov-Jessen, L., Villadsen, R., Edwards, J.C., Petersen, O.W. Am. J. Pathol. (2002)
- Identification of chloride intracellular channel proteins in spermatozoa. Myers, K., Somanath, P.R., Berryman, M., Vijayaraghavan, S. FEBS Lett. (2004)
- Crystal structure of a soluble form of the intracellular chloride ion channel CLIC1 (NCC27) at 1.4-A resolution. Harrop, S.J., DeMaere, M.Z., Fairlie, W.D., Reztsova, T., Valenzuela, S.M., Mazzanti, M., Tonini, R., Qiu, M.R., Jankova, L., Warton, K., Bauskin, A.R., Wu, W.M., Pankhurst, S., Campbell, T.J., Breit, S.N., Curmi, P.M. J. Biol. Chem. (2001)
- Redox regulation of CLIC1 by cysteine residues associated with the putative channel pore. Singh, H., Ashley, R.H. Biophys. J. (2006)
- CLIC1 inserts from the aqueous phase into phospholipid membranes, where it functions as an anion channel. Tulk, B.M., Kapadia, S., Edwards, J.C. Am. J. Physiol., Cell Physiol. (2002)
- NCC27, a homolog of intracellular Cl- channel p64, is expressed in brush border of renal proximal tubule. Tulk, B.M., Edwards, J.C. Am. J. Physiol. (1998)
- Interaction of Sedlin with chloride intracellular channel proteins. Fan, L., Yu, W., Zhu, X. FEBS Lett. (2003)
- CLIC4, an intracellular chloride channel protein, is a novel molecular target for cancer therapy. Suh, K.S., Mutoh, M., Gerdes, M., Yuspa, S.H. J. Investig. Dermatol. Symp. Proc. (2005)
- Genomic structure of a novel chloride channel gene, CLIC2, in Xq28. Heiss, N.S., Poustka, A. Genomics (1997)
- Molecular cloning and characterization of a mitogen-activated protein kinase-associated intracellular chloride channel. Qian, Z., Okuhara, D., Abe, M.K., Rosner, M.R. J. Biol. Chem. (1999)
- Development of a new epitope tag recognized by a monoclonal antibody to Rickettsia typhi. Lee, J.R., Chang, Y.Y., Hahn, M.J. BioTechniques (2001)
- Molecular cloning and expression of a chloride ion channel of cell nuclei. Valenzuela, S.M., Martin, D.K., Por, S.B., Robbins, J.M., Warton, K., Bootcov, M.R., Schofield, P.R., Campbell, T.J., Breit, S.N. J. Biol. Chem. (1997)
- Crystal structure of the soluble form of the redox-regulated chloride ion channel protein CLIC4. Littler, D.R., Assaad, N.N., Harrop, S.J., Brown, L.J., Pankhurst, G.J., Luciani, P., Aguilar, M.I., Mazzanti, M., Berryman, M.A., Breit, S.N., Curmi, P.M. FEBS J. (2005)