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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

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Gene Review: 

MED30  -  mediator complex subunit 30

Homo sapiens

Synonyms: MED30S, Mediator complex subunit 30, Mediator of RNA polymerase II transcription subunit 30, THRAP6, TRAP/Mediator complex component TRAP25, ...
 
 
 
 
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High impact information on THRAP6

  • An antibody that is specific for TRAP25 allowed quantitative immunodepletion of essentially all TRAP/Mediator components from HeLa nuclear extract, without detectably affecting levels of RNA polymerase II and corresponding general transcription factors [1].

References

  1. Requirement of TRAP/mediator for both activator-independent and activator-dependent transcription in conjunction with TFIID-associated TAF(II)s. Baek, H.J., Malik, S., Qin, J., Roeder, R.G. Mol. Cell. Biol. (2002) [Pubmed]
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