Chemical Compound Review:
Mediator 2-[1-[3-(trifluoromethyl) phenyl]propan-2...
Synonyms:
Mediaxal, Balans, Lipophoral, Benfluorex HCl, Prestwick_911, ...
This record was replaced with 2318.
- Mammalian Srb/Mediator complex is targeted by adenovirus E1A protein. Boyer, T.G., Martin, M.E., Lees, E., Ricciardi, R.P., Berk, A.J. Nature (1999)
- Head module control of mediator interactions. Takagi, Y., Calero, G., Komori, H., Brown, J.A., Ehrensberger, A.H., Hudmon, A., Asturias, F., Kornberg, R.D. Mol. Cell (2006)
- Recruitment of TFIIH to the HIV LTR is a rate-limiting step in the emergence of HIV from latency. Kim, Y.K., Bourgeois, C.F., Pearson, R., Tyagi, M., West, M.J., Wong, J., Wu, S.Y., Chiang, C.M., Karn, J. EMBO J. (2006)
- Principal role of TRAP/mediator and SWI/SNF complexes in Kaposi's sarcoma-associated herpesvirus RTA-mediated lytic reactivation. Gwack, Y., Baek, H.J., Nakamura, H., Lee, S.H., Meisterernst, M., Roeder, R.G., Jung, J.U. Mol. Cell. Biol. (2003)
- Gambling Control Self-efficacy as a Mediator of the Effects of Low Emotional Intelligence on Problem Gambling. Kaur, I., Schutte, N.S., Thorsteinsson, E.B. Journal of gambling studies / co-sponsored by the National Council on Problem Gambling and Institute for the Study of Gambling and Commercial Gaming (2006)
- Mediator of transcriptional regulation. Myers, L.C., Kornberg, R.D. Annu. Rev. Biochem. (2000)
- A recurrent mutation in MED12 leading to R961W causes Opitz-Kaveggia syndrome. Risheg, H., Graham, J.M., Clark, R.D., Rogers, R.C., Opitz, J.M., Moeschler, J.B., Peiffer, A.P., May, M., Joseph, S.M., Jones, J.R., Stevenson, R.E., Schwartz, C.E., Friez, M.J. Nat. Genet. (2007)
- The RNA polymerase II machinery: structure illuminates function. Woychik, N.A., Hampsey, M. Cell (2002)
- Transcription coactivator TRAP220 is required for PPAR gamma 2-stimulated adipogenesis. Ge, K., Guermah, M., Yuan, C.X., Ito, M., Wallberg, A.E., Spiegelman, B.M., Roeder, R.G. Nature (2002)
- A component of the ARC/Mediator complex required for TGF beta/Nodal signalling. Kato, Y., Habas, R., Katsuyama, Y., Näär, A.M., He, X. Nature (2002)
- The Role of Decay-accelerating Factor as a Receptor for Helicobacter pylori and a Mediator of Gastric Inflammation. O'brien, D.P., Israel, D.A., Krishna, U., Romero-Gallo, J., Nedrud, J., Medof, M.E., Lin, F., Redline, R., Lublin, D.M., Nowicki, B.J., Franco, A.T., Ogden, S., Williams, A.D., Polk, D.B., Peek, R.M. J. Biol. Chem. (2006)
- Histamine, But Not Leukotriene C4, is an Essential Mediator in Cold Urticaria Wheals. Nuutinen, P., Harvima, I.T., Ackermann, L. Acta Derm. Venereol. (2007)
- Coactivator cross-talk specifies transcriptional output. Marr, M.T., Isogai, Y., Wright, K.J., Tjian, R. Genes Dev. (2006)
- The Swi5 activator recruits the Mediator complex to the HO promoter without RNA polymerase II. Bhoite, L.T., Yu, Y., Stillman, D.J. Genes Dev. (2001)
- Mrc1 is a replication fork component whose phosphorylation in response to DNA replication stress activates Rad53. Osborn, A.J., Elledge, S.J. Genes Dev. (2003)
- Thyroid hormone-induced juxtaposition of regulatory elements/factors and chromatin remodeling of Crabp1 dependent on MED1/TRAP220. Park, S.W., Li, G., Lin, Y.P., Barrero, M.J., Ge, K., Roeder, R.G., Wei, L.N. Mol. Cell (2005)
- Association of the Mediator complex with enhancers of active genes. Kuras, L., Borggrefe, T., Kornberg, R.D. Proc. Natl. Acad. Sci. U.S.A. (2003)
- The TRAP/Mediator coactivator complex interacts directly with estrogen receptors alpha and beta through the TRAP220 subunit and directly enhances estrogen receptor function in vitro. Kang, Y.K., Guermah, M., Yuan, C.X., Roeder, R.G. Proc. Natl. Acad. Sci. U.S.A. (2002)
- Characterization of mediator complexes from HeLa cell nuclear extract. Wang, G., Cantin, G.T., Stevens, J.L., Berk, A.J. Mol. Cell. Biol. (2001)
- A role for cofactor-cofactor and cofactor-histone interactions in targeting p300, SWI/SNF and Mediator for transcription. Huang, Z.Q., Li, J., Sachs, L.M., Cole, P.A., Wong, J. EMBO J. (2003)
- Ordered recruitment of histone acetyltransferases and the TRAP/Mediator complex to thyroid hormone-responsive promoters in vivo. Sharma, D., Fondell, J.D. Proc. Natl. Acad. Sci. U.S.A. (2002)
- Independent recruitment of mediator and SAGA by the activator Met4. Leroy, C., Cormier, L., Kuras, L. Mol. Cell. Biol. (2006)
- ChREBP*Mlx Is the Principal Mediator of Glucose-induced Gene Expression in the Liver. Ma, L., Robinson, L.N., Towle, H.C. J. Biol. Chem. (2006)
- Evidence against Calcium as a Mediator of Mitochondrial Dysfunction during Apoptosis Induced by Arachidonic Acid and Other Free Fatty Acids. Maia, R.C., Culver, C.A., Laster, S.M. J. Immunol. (2006)
- TFIIH is negatively regulated by cdk8-containing mediator complexes. Akoulitchev, S., Chuikov, S., Reinberg, D. Nature (2000)
- MED1/TRAP220 exists predominantly in a TRAP/ Mediator subpopulation enriched in RNA polymerase II and is required for ER-mediated transcription. Zhang, X., Krutchinsky, A., Fukuda, A., Chen, W., Yamamura, S., Chait, B.T., Roeder, R.G. Mol. Cell (2005)
- Targeting of Swi/Snf to the yeast GAL1 UAS G requires the Mediator, TAF IIs, and RNA polymerase II. Lemieux, K., Gaudreau, L. EMBO J. (2004)
- Site-specific Srb10-dependent phosphorylation of the yeast Mediator subunit Med2 regulates gene expression from the 2-microm plasmid. Hallberg, M., Polozkov, G.V., Hu, G.Z., Beve, J., Gustafsson, C.M., Ronne, H., Björklund, S. Proc. Natl. Acad. Sci. U.S.A. (2004)
- Activator-specific requirement of yeast mediator proteins for RNA polymerase II transcriptional activation. Han, S.J., Lee, Y.C., Gim, B.S., Ryu, G.H., Park, S.J., Lane, W.S., Kim, Y.J. Mol. Cell. Biol. (1999)
- Conserved structures of mediator and RNA polymerase II holoenzyme. Asturias, F.J., Jiang, Y.W., Myers, L.C., Gustafsson, C.M., Kornberg, R.D. Science (1999)
- In vivo target of a transcriptional activator revealed by fluorescence resonance energy transfer. Bhaumik, S.R., Raha, T., Aiello, D.P., Green, M.R. Genes Dev. (2004)
- Genome-wide occupancy profile of mediator and the Srb8-11 module reveals interactions with coding regions. Zhu, X., Wirén, M., Sinha, I., Rasmussen, N.N., Linder, T., Holmberg, S., Ekwall, K., Gustafsson, C.M. Mol. Cell (2006)
- RNA polymerase II structure, and organization of the preinitiation complex. Asturias, F.J. Curr. Opin. Struct. Biol. (2004)
- The activator-recruited cofactor/Mediator coactivator subunit ARC92 is a functionally important target of the VP16 transcriptional activator. Yang, F., DeBeaumont, R., Zhou, S., Näär, A.M. Proc. Natl. Acad. Sci. U.S.A. (2004)