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Gene Review

proC  -  pyrroline-5-carboxylate reductase

Escherichia coli O157:H7 str. Sakai

 
 
 
 
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Disease relevance of proC

  • Human P5CR was over-expressed in Escherichia coli and purified to homogeneity by chromatography [1].
 

High impact information on proC

  • Pyrroline-5-carboxylate reductase (P5CR) catalyzes the reduction of Delta1-pyrroline-5-carboxylate (P5C) to proline with concomitant oxidation of NAD(P)H to NAD(P)(+) [1].
 

Analytical, diagnostic and therapeutic context of proC

  • Purification, characterization, and crystallization of human pyrroline-5-carboxylate reductase [1].

References

  1. Purification, characterization, and crystallization of human pyrroline-5-carboxylate reductase. Meng, Z., Lou, Z., Liu, Z., Hui, D., Bartlam, M., Rao, Z. Protein Expr. Purif. (2006) [Pubmed]
 
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