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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
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Disease relevance of Crystallization


Psychiatry related information on Crystallization


High impact information on Crystallization

  • With a reversed isotope dilution technic with crystallization to constant specific activity, we showed the tumor tissue to convert dehydroepiandrosterone sulfate and dehydroepiandrosterone to estrone and estradiol [8].
  • Under the same conditions of dietary and fluid intake the urine samples of the patients with stone formation were more supersaturated with calcium oxalate (P less than 0.001) and had lower concentrations of protective inhibitors of crystallization (P less than 0.001) than those of the controls [9].
  • Here, however, we report the distributions of trace elements within pyroxenes of the Shergotty meteorite--a basalt body ejected 175 million years ago from Mars--as well as hydrous and anhydrous crystallization experiments that, together, imply that water contents of pre-eruptive magma on Mars could have been up to 1.8% [10].
  • We interpret the silicate-enclosed sulphides as the residues of melting processes and interstitial sulphides as the crystallization products of sulphide-bearing (metasomatic) fluids [11].
  • Testosterone seems to be required for song crystallization, however [12].

Chemical compound and disease context of Crystallization


Biological context of Crystallization


Anatomical context of Crystallization


Associations of Crystallization with chemical compounds


Gene context of Crystallization


Analytical, diagnostic and therapeutic context of Crystallization


  1. Manipulating phospholipids for crystallization of a membrane transport protein. Guan, L., Smirnova, I.N., Verner, G., Nagamori, S., Kaback, H.R. Proc. Natl. Acad. Sci. U.S.A. (2006) [Pubmed]
  2. Crystals of hemagglutinin-neuraminidase of parainfluenza virus contain triple-stranded helices. Murti, K.G., Takimoto, T., Laver, W.G., Portner, A. Proc. Natl. Acad. Sci. U.S.A. (1993) [Pubmed]
  3. Cholesterol crystallization in human gallbladder bile: relation to gallstone number, bile composition, and apolipoprotein E4 isoform. Van Erpecum, K.J., Van Berge-henegouwen, G.P., Eckhardt, E.R., Portincasa, P., Van De Heijning, B.J., Dallinga-Thie, G.M., Groen, A.K. Hepatology (1998) [Pubmed]
  4. Crystallization and properties of L-arginine deiminase of Pseudomonas putida. Shibatani, T., Kakimoto, T., Chibata, I. J. Biol. Chem. (1975) [Pubmed]
  5. Probability analysis of variational crystallization and its application to gp120, the exterior envelope glycoprotein of type 1 human immunodeficiency virus (HIV-1). Kwong, P.D., Wyatt, R., Desjardins, E., Robinson, J., Culp, J.S., Hellmig, B.D., Sweet, R.W., Sodroski, J., Hendrickson, W.A. J. Biol. Chem. (1999) [Pubmed]
  6. Synthesis of dawsonite: a method to treat the etching waste streams of the aluminium anodising industry. Alvarez-Ayuso, E., Nugteren, H.W. Water Res. (2005) [Pubmed]
  7. Circadian variations in the risk of urinary calcium oxalate stone formation. Robert, M., Roux, J.O., Bourelly, F., Boularan, A.M., Guiter, J., Monnier, L. British journal of urology. (1994) [Pubmed]
  8. Mechanism of feminization in primary liver cancer. Kew, M.C., Kirschner, M.A., Abrahams, G.E., Katz, M. N. Engl. J. Med. (1977) [Pubmed]
  9. Saturation-inhibition index as a measure of the risk of calcium oxalate stone formation in the urinary tract. Robertson, W.G., Peacock, M., Marshall, R.W., Marshall, D.H., Nordin, B.E. N. Engl. J. Med. (1976) [Pubmed]
  10. Geochemical evidence for magmatic water within Mars from pyroxenes in the Shergotty meteorite. McSween, H.Y., Grove, T.L., Lentz, R.C., Dann, J.C., Holzheid, A.H., Riciputi, L.R., Ryan, J.G. Nature (2001) [Pubmed]
  11. Non-chondritic distribution of the highly siderophile elements in mantle sulphides. Alard, O., Griffin, W.L., Lorand, J.P., Jackson, S.E., O'Reilly, S.Y. Nature (2000) [Pubmed]
  12. The role of sex steroids in the acquisition and production of birdsong. Marler, P., Peters, S., Ball, G.F., Dufty, A.M., Wingfield, J.C. Nature (1988) [Pubmed]
  13. X-ray crystallographic studies of the alanine-specific racemase from Bacillus stearothermophilus. Overproduction, crystallization, and preliminary characterization. Neidhart, D.J., Distefano, M.D., Tanizawa, K., Soda, K., Walsh, C.T., Petsko, G.A. J. Biol. Chem. (1987) [Pubmed]
  14. Crystallographic data for Streptomyces avidinii streptavidin. Weber, P.C., Cox, M.J., Salemme, F.R., Ohlendorf, D.H. J. Biol. Chem. (1987) [Pubmed]
  15. Effect of angiotensin II receptor blockage on osteopontin expression and calcium oxalate crystal deposition in rat kidneys. Umekawa, T., Hatanaka, Y., Kurita, T., Khan, S.R. J. Am. Soc. Nephrol. (2004) [Pubmed]
  16. Physicochemical action of potassium-magnesium citrate in nephrolithiasis. Pak, C.Y., Koenig, K., Khan, R., Haynes, S., Padalino, P. J. Bone Miner. Res. (1992) [Pubmed]
  17. Effect of oral purine load and allopurinol on the crystallization of calcium salts in urine of patients with hyperuricosuric calcium urolithiasis. Pak, C.Y., Barilla, D.E., Holt, K., Brinkley, L., Tolentino, R., Zerwekh, J.E. Am. J. Med. (1978) [Pubmed]
  18. Crystallographic snapshots of a replicative DNA polymerase encountering an abasic site. Hogg, M., Wallace, S.S., Doublié, S. EMBO J. (2004) [Pubmed]
  19. Carcinoembryonic antigen-related cell adhesion molecule 1 is the 85-kilodalton pronase-resistant biliary glycoprotein in the cholesterol crystallization promoting low density protein-lipid complex. Jirsa, M., Muchová, L., Dráberová, L., Dráber, P., Smíd, F., Kuroki, M., Marecek, Z., Groen, A.K. Hepatology (2001) [Pubmed]
  20. Molecular analysis of cellulose biosynthesis in Arabidopsis. Arioli, T., Peng, L., Betzner, A.S., Burn, J., Wittke, W., Herth, W., Camilleri, C., Höfte, H., Plazinski, J., Birch, R., Cork, A., Glover, J., Redmond, J., Williamson, R.E. Science (1998) [Pubmed]
  21. Filamentous, helical, and tubular microstructures during cholesterol crystallization from bile. Evidence that cholesterol does not nucleate classic monohydrate plates. Konikoff, F.M., Chung, D.S., Donovan, J.M., Small, D.M., Carey, M.C. J. Clin. Invest. (1992) [Pubmed]
  22. Crystal structure of the extracellular domain from P0, the major structural protein of peripheral nerve myelin. Shapiro, L., Doyle, J.P., Hensley, P., Colman, D.R., Hendrickson, W.A. Neuron (1996) [Pubmed]
  23. Electron microscopic evidence for nucleation and growth of 3D acetylcholine receptor microcrystals in structured lipid-detergent matrices. Paas, Y., Cartaud, J., Recouvreur, M., Grailhe, R., Dufresne, V., Pebay-Peyroula, E., Landau, E.M., Changeux, J.P. Proc. Natl. Acad. Sci. U.S.A. (2003) [Pubmed]
  24. Purification and crystallization of creatine kinase from rabbit skeletal muscle. Hershenson, S., Helmers, N., Desmueles, P., Stroud, R. J. Biol. Chem. (1986) [Pubmed]
  25. Basic guide to the mechanisms of antiestrogen action. MacGregor, J.I., Jordan, V.C. Pharmacol. Rev. (1998) [Pubmed]
  26. A new subgroup of lectin-bound biliary proteins binds to cholesterol crystals, modifies crystal morphology, and inhibits cholesterol crystallization. Busch, N., Lammert, F., Marschall, H.U., Matern, S. J. Clin. Invest. (1995) [Pubmed]
  27. Identification of human biliary alpha 1-acid glycoprotein as a cholesterol crystallization promoter. Abei, M., Nuutinen, H., Kawczak, P., Schwarzendrube, J., Pillay, S.P., Holzbach, R.T. Gastroenterology (1994) [Pubmed]
  28. Cyclic nucleotides and glycoproteins during formation of cholesterol gallstones in prairie dogs. Zak, R.A., Frenkiel, P.G., Marks, J.W., Bonorris, G.G., Allen, A., Schoenfield, L.J. Gastroenterology (1984) [Pubmed]
  29. The crystal structures of chloramphenicol phosphotransferase reveal a novel inactivation mechanism. Izard, T., Ellis, J. EMBO J. (2000) [Pubmed]
  30. Effects of phosphorylation of threonine 160 on cyclin-dependent kinase 2 structure and activity. Brown, N.R., Noble, M.E., Lawrie, A.M., Morris, M.C., Tunnah, P., Divita, G., Johnson, L.N., Endicott, J.A. J. Biol. Chem. (1999) [Pubmed]
  31. The structure of the multidrug resistance protein 1 (MRP1/ABCC1). crystallization and single-particle analysis. Rosenberg, M.F., Mao, Q., Holzenburg, A., Ford, R.C., Deeley, R.G., Cole, S.P. J. Biol. Chem. (2001) [Pubmed]
  32. Purification and crystallization of the cystic fibrosis transmembrane conductance regulator (CFTR). Rosenberg, M.F., Kamis, A.B., Aleksandrov, L.A., Ford, R.C., Riordan, J.R. J. Biol. Chem. (2004) [Pubmed]
  33. In the absence of type III receptor, the transforming growth factor (TGF)-beta type II-B receptor requires the type I receptor to bind TGF-beta2. del Re, E., Babitt, J.L., Pirani, A., Schneyer, A.L., Lin, H.Y. J. Biol. Chem. (2004) [Pubmed]
  34. Aragonite crystallization in primary cell cultures of multicellular isolates from a hard coral, Pocillopora damicornis. Domart-Coulon, I.J., Elbert, D.C., Scully, E.P., Calimlim, P.S., Ostrander, G.K. Proc. Natl. Acad. Sci. U.S.A. (2001) [Pubmed]
  35. An integrated approach to structural genomics. Heinemann, U., Frevert, J., Hofmann, K., Illing, G., Maurer, C., Oschkinat, H., Saenger, W. Prog. Biophys. Mol. Biol. (2000) [Pubmed]
  36. Mechanism of preferential enrichment, an unusual enantiomeric resolution phenomenon caused by polymorphic transition during crystallization of mixed crystals composed of two enantiomers. Tamura, R., Fujimoto, D., Lepp, Z., Misaki, K., Miura, H., Takahashi, H., Ushio, T., Nakai, T., Hirotsu, K. J. Am. Chem. Soc. (2002) [Pubmed]
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