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Gene Review

cma2  -  cyclopropane-fatty-acyl-phospholipid synthase

Mycobacterium tuberculosis CDC1551

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Disease relevance of cma2

  • Expression of cma2 in Mycobacterium smegmatis resulted in the cyclopropanation of the proximal double bond in the alpha 1 series of mycolic acids [1].

High impact information on cma2

  • This gene, named cma2, was sequenced and found to be 52% identical to cma1 (which cyclopropanates the distal double bond) and 73% identical to the gene from M. leprae [1].


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