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Gene Review

D7L  -  ankyrin-like protein

Monkeypox virus Zaire-96-I-16

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Disease relevance of D7L

  • The host range of Variola virus is limited to humans and thus the affinity of D7L for IL-18 does not correlate with its host range [1].

High impact information on D7L

  • Importantly, D7L interacted with both GAG and IL-18 simultaneously, indicating that the binding sites were distinct [1].


  1. Interleukin-18 and glycosaminoglycan binding by a protein encoded by Variola virus. Esteban, D.J., Nuara, A.A., Buller, R.M. J. Gen. Virol. (2004) [Pubmed]
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