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Gene Review:

SLC22A13 - solute carrier family 22 (organic...

Homo sapiens

Synonyms: OAT10, OCTL1, OCTL3, ORCTL-3, ORCTL3, ...

Nishiwaki, T. et al., Liberg, D. et al.

Liberg, Sigvardsson, Leanderson,

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High impact information on SLC22A13

The two genes are clustered within a 52-kb region of genomic DNA and ORCTL4 lies about 27 kb telomeric to ORCTL3 in the genomic DNA sequence in a tail-to-head orientation [1].
The 3' flanking sequence of kappa promoter octamers was found to contain either a conserved A or G residue which increased the affinity of the octamer core motif for Octl and Oct2A [2].

Other interactions of SLC22A13

Molecular cloning, mapping, and characterization of two novel human genes, ORCTL3 and ORCTL4, bearing homology to organic-cation transporters [1].

References

Molecular cloning, mapping, and characterization of two novel human genes, ORCTL3 and ORCTL4, bearing homology to organic-cation transporters. Nishiwaki, T., Daigo, Y., Tamari, M., Fujii, Y., Nakamura, Y. Cytogenet. Cell Genet. (1998) [Pubmed]
Oct proteins are qualitative rather than quantitative regulators of kappa transcription. Liberg, D., Sigvardsson, M., Leanderson, T. Mol. Immunol. (1997) [Pubmed]

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