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PDB4  -  Paget disease of bone 4

Homo sapiens

 
 
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High impact information on PDB4

  • It is proposed that the 5q35-qter and 5q31 loci be named "PDB3" and "PDB4," respectively [1].
  • The expression level of Tslc1 was significantly reduced in PDAs (p<0.05) compared with normal pancreatic tissues [2].
  • The expression of the E-cadherin was significantly reduced in PDAs (p<0.05) compared with normal pancreatic tissue [3].

References

  1. Paget disease of bone: mapping of two loci at 5q35-qter and 5q31. Laurin, N., Brown, J.P., Lemainque, A., Duchesne, A., Huot, D., Lacourcière, Y., Drapeau, G., Verreault, J., Raymond, V., Morissette, J. Am. J. Hum. Genet. (2001) [Pubmed]
  2. Aberrant DNA methylation of the 5' upstream region of Tslc1 gene in hamster pancreatic tumors. Shimizu, K., Onishi, M., Sugata, E., Fujii, H., Honoki, K., Tsujiuchi, T. Biochem. Biophys. Res. Commun. (2007) [Pubmed]
  3. Reduced expression of the E-cadherin gene and its aberrant DNA methylation in hamster pancreatic tumors. Shimizu, K., Hanaoka, M., Kato, A., Fujii, H., Honoki, K., Tsujiuchi, T. Biochem. Biophys. Res. Commun. (2005) [Pubmed]
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