The world's first wiki where authorship really matters (Nature Genetics, 2008). Due credit and reputation for authors. Imagine a global collaborative knowledge base for original thoughts. Search thousands of articles and collaborate with scientists around the globe.

wikigene or wiki gene protein drug chemical gene disease author authorship tracking collaborative publishing evolutionary knowledge reputation system wiki2.0 global collaboration genes proteins drugs chemicals diseases compound
Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

Editor

Share

Personal info

View

Links

  • Homologues
  • NCBI Gene
  • NCBI SNP
  • iHOP resource
  • OMIM
  • SNPedia
  • UniProt
  • Ensembl
  • HGNC

Table of contents

About

Terms

 

Gene Review: 

MED27  -  mediator complex subunit 27

Homo sapiens

Synonyms: CRAP34, CRSP complex subunit 8, CRSP34, CRSP8, Cofactor required for Sp1 transcriptional activation subunit 8, ...
 
 
 
 
Welcome! If you are familiar with the subject of this article, you can contribute to this open access knowledge base by deleting incorrect information, restructuring or completely rewriting any text. Read more.
 

High impact information on CRSP8

  • Confirmation of the antiplatelet effect was obtained through in vitro human thromboxane B2(TXB2) synthase inhibition and MED 27 was very active compared with various non-steroidal anti-inflammatories (NSAIDs) [1].
  • MED 27 ex vivo induced a dose-dependent inhibition of rat platelet aggregation at doses much lower than that of acetylsalicylic acid (ASA) [1].
  • The effect on platelets of a new molecule denominated MED 27 (1-methyl-5-(4-methylbenzoyl)pyrrole-2-acetic acid 2-(theophylline-7-yl)ethyl ester, CAS 104333-87-1) was investigated [1].

References

  1. Antiplatelet effect of a new inhibitor of thromboxane synthase and thromboxane A2 receptors. Tubaro, E., Belogi, L., Mezzadri, C.M. Arzneimittel-Forschung. (1996) [Pubmed]
Contributions to this collaborative article are from individual authors of WikiGenes or mined by the WikiGenes Data Mining Engine from MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.About WikiGenesOpen Access LicencePrivacy PolicyTerms of Useapsburg
 
WikiGenes - Universities