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Gene Review:

dinI - DNA damage-inducible protein I

Escherichia coli str. K-12 substr. MG1655

Synonyms: ECK1046, JW1048

Berkmen, M. et al., Yasuda, T. et al.

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Disease relevance of dinI

The dinI homolog of S. marcescens was cloned from a plasmid library by virtue of its ability to inhibit nuclease expression from the S. marcescens nucA gene integrated in the genome of E. coli [1].

High impact information on dinI

Three different BamHI fragments were found to suppress cold sensitivity, and the lexA, dinG, and dinI genes were identified to be responsible for the suppression in each fragment [2].

References

Multi-copy repression of Serratia marcescens nuclease expression by dinI. Berkmen, M., Benedik, M.J. Curr. Microbiol. (2002) [Pubmed]
Multicopy suppressors of the cold-sensitive phenotype of the pcsA68 (dinD68) mutation in Escherichia coli. Yasuda, T., Nagata, T., Ohmori, H. J. Bacteriol. (1996) [Pubmed]

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