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Gene Review

perR  -  CP4-6 prophage; putative DNA-binding...

Escherichia coli str. K-12 substr. MG1655

Synonyms: ECK0256, JW0244
 
 
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High impact information on perR

  • Transcription of perR was autoregulated, and PerR repressed transcription of the iron homeostasis regulator Fur, which is a positive regulator of catalase expression [1].
  • A knock-out mutant of the gene encoding the transcription factor (perR) constitutively expressed mrgA, and its nucleoid was compacted without the oxidative stresses [2].

References

  1. PerR controls oxidative stress resistance and iron storage proteins and is required for virulence in Staphylococcus aureus. Horsburgh, M.J., Clements, M.O., Crossley, H., Ingham, E., Foster, S.J. Infect. Immun. (2001) [Pubmed]
  2. Bacterial nucleoid dynamics: oxidative stress response in Staphylococcus aureus. Morikawa, K., Ohniwa, R.L., Kim, J., Maruyama, A., Ohta, T., Takeyasu, K. Genes Cells (2006) [Pubmed]
 
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