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Gene Review

otsB  -  trehalose-6-phosphate phosphatase,...

Escherichia coli str. K-12 substr. MG1655

Synonyms: ECK1896, JW1886, otsP
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High impact information on otsB

  • Primer extension analysis showed only one transcription start point upstream from otsB and one upstream from otsA, regardless of the growth conditions tested [1].
  • The araH gene is located directly upstream from otsBA, and otsB may be identical to pexA [1].
  • In contrast, transformation with otsB, which encodes trehalose phosphate phosphatase or Trec, encoding trehalose phosphate hydrolase, produced the opposite effect [2].

Analytical, diagnostic and therapeutic context of otsB


  1. Analysis of the otsBA operon for osmoregulatory trehalose synthesis in Escherichia coli and homology of the OtsA and OtsB proteins to the yeast trehalose-6-phosphate synthase/phosphatase complex. Kaasen, I., McDougall, J., Strøm, A.R. Gene (1994) [Pubmed]
  2. Genetic modification of photosynthesis with E. coli genes for trehalose synthesis. Pellny, T.K., Ghannoum, O., Conroy, J.P., Schluepmann, H., Smeekens, S., Andralojc, J., Krause, K.P., Goddijn, O., Paul, M.J. Plant Biotechnol. J. (2004) [Pubmed]
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