Disease relevance of mreC

• New mre genes mreC and mreD, responsible for formation of the rod shape of Escherichia coli cells [1].

High impact information on mreC

• The initiation codon of the mreD gene overlaps the termination codon of the mreC gene by one nucleotide residue [1].
• The mreC gene is preceded by the mreB gene and by a 65-base-pair spacing sequence containing a palindrome sequence and a possible Shine-Dalgarno sequence [1].

Biological context of mreC

• New shape-determining genes in the mre cluster at 71 min on the Escherichia coli chromosome map, named mreC and mreD, were identified by complementation experiments using delta mre-678 mutant cells, which have a 5-kilobase-pair deletion encompassing the mre region, and by DNA sequencing [1].

References