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Gene Review:

ftsY - Signal Recognition Particle (SRP) receptor

Escherichia coli str. K-12 substr. MG1655

Synonyms: ECK3448, JW3429

Gill, D.R. et al., Taha, M.K. et al., Arvidson, C.G. et al.

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Disease relevance of ftsY

The identification of the Escherichia coli ftsY gene product: an unusual protein [1].

High impact information on ftsY

Complementation tests indicated the presence of a promoter within ftsY required for expression of ftsE and ftsX [1].
Low-level expression of pilA in an ftsY conditional mutant can complement the ftsY mutation and restore normal growth to this strain under nonpermissive conditions [2].
We also examined the interference of pilA expression in E. coli with the function of the products of ftsY and ffh and observed an accumulation of pre-beta-lactamase [3].

References

The identification of the Escherichia coli ftsY gene product: an unusual protein. Gill, D.R., Salmond, G.P. Mol. Microbiol. (1990) [Pubmed]
Neisseria gonorrhoeae PilA is an FtsY homolog. Arvidson, C.G., Powers, T., Walter, P., So, M. J. Bacteriol. (1999) [Pubmed]
Role of pilA, an essential regulatory gene of Neisseria gonorrhoeae, in the stress response. Taha, M.K., Larribe, M., Dupuy, B., Giorgini, D., Marchal, C. J. Bacteriol. (1992) [Pubmed]

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