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Gene Review:

frdB - fumarate reductase (anaerobic), Fe-S subunit

Escherichia coli str. K-12 substr. MG1655

Synonyms: ECK4149, JW4114

Cole, S.T. et al., Lauterbach, F. et al., Lauterbach, F. et al.

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Disease relevance of frdB

Location and nucleotide sequence of frdB, the gene coding for the iron-sulphur protein subunit of the fumarate reductase of Escherichia coli [1].
The fumarate reductase operon of Wolinella succinogenes. Sequence and expression of the frdA and frdB genes [2].

Biological context of frdB

The frdB gene, encoding the iron-sulphur protein subunit of fumarate reductase, has been located and its complete nucleotide sequence determined [1].
The frdA and frdB genes are present only once in the genome [3].

Associations of frdB with chemical compounds

The genes frdA and frdB, which encode the FAD protein (Frd A, Mr 79,000) and the iron-sulfur protein (Frd B, Mr 31,000) of the fumarate reductase complex, were cloned together with a W. succinogenes promoter [3].

References

Location and nucleotide sequence of frdB, the gene coding for the iron-sulphur protein subunit of the fumarate reductase of Escherichia coli. Cole, S.T., Grundström, T., Jaurin, B., Robinson, J.J., Weiner, J.H. Eur. J. Biochem. (1982) [Pubmed]
The fumarate reductase operon of Wolinella succinogenes. Sequence and expression of the frdA and frdB genes. Lauterbach, F., Körtner, C., Albracht, S.P., Unden, G., Kröger, A. Arch. Microbiol. (1990) [Pubmed]
Cloning and expression of the genes of two fumarate reductase subunits from Wolinella succinogenes. Lauterbach, F., Körtner, C., Tripier, D., Unden, G. Eur. J. Biochem. (1987) [Pubmed]

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