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Gene Review:

chpS - antitoxin of the ChpBS toxin-antitoxin system

Escherichia coli str. K-12 substr. MG1655

Synonyms: ECK4220, JW5750, chpBI, yjfB

Masuda, Y. et al., Zhang, Y. et al.

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Disease relevance of chpS

We then constructed mutants with an insertion of a (cat) fragment within chpBK or chpBI on the E. coli chromosome [1].

High impact information on chpS

This module consists of a pair of genes, chpBI and chpBK encoding antitoxin ChpBI and toxin ChpBK, respectively [2].

References

Mapping and disruption of the chpB locus in Escherichia coli. Masuda, Y., Ohtsubo, E. J. Bacteriol. (1994) [Pubmed]
Characterization of ChpBK, an mRNA interferase from Escherichia coli. Zhang, Y., Zhu, L., Zhang, J., Inouye, M. J. Biol. Chem. (2005) [Pubmed]

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