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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

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Gene Review: 

PGS1  -  phosphatidylglycerophosphate synthase 1

Homo sapiens

Synonyms: CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase, mitochondrial, DKFZP762M186, PGP synthase 1, Phosphatidylglycerophosphate synthase 1
 
 
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Disease relevance of PGS1

  • The molecular orientation in a lipid membrane of the peptide fragment VEYAGIALFFVAAVLTLWSMLQYLSAAR (phosphatidylglycerophosphate synthase (Pgs) peptide E) of an integral membrane protein, Pgs, in Escherichia coli has been investigated by solid-state 15N nuclear magnetic resonance (NMR) on macroscopically aligned lipid bilayers [1].
 

High impact information on PGS1

References

  1. Influence of transmembrane peptides on bilayers of phosphatidylcholines with different acyl chain lengths studied by solid-state NMR. Byström, T., Strandberg, E., Kovacs, F.A., Cross, T.A., Lindblom, G. Biochim. Biophys. Acta (2000) [Pubmed]
  2. A somatic cell mutant defective in phosphatidylglycerophosphate synthase, with impaired phosphatidylglycerol and cardiolipin biosynthesis. Ohtsuka, T., Nishijima, M., Akamatsu, Y. J. Biol. Chem. (1993) [Pubmed]
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