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Gene Review

hupB  -  HU, DNA-binding transcriptional regulator,...

Escherichia coli str. K-12 substr. MG1655

Synonyms: ECK0434, JW0430, dpeA, hopD
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Disease relevance of hupB


High impact information on hupB

  • Upon introduction of an HU-overproducing plasmid carrying either the hupB or the hupA gene into the wild-type and hup single deletion mutants, the intracellular levels of mRNA from the chromosomal hup genes are reduced [1].
  • Both hupB and hupA genes possess a DNA sequence with a rho-independent transcriptional terminator in their respective regions downstream from the coding regions [1].


  1. Promoters and autogenous control of the Escherichia coli hupA and hupB genes. Kohno, K., Wada, M., Kano, Y., Imamoto, F. J. Mol. Biol. (1990) [Pubmed]
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