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Gene Review:

dld - D-lactate dehydrogenase

Haemophilus influenzae Rd KW20

Denicola-Seoane, A. et al., Denicola-Seoane, A. et al.

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Disease relevance of dld

Purification and characterization of Haemophilus influenzae D-lactate dehydrogenase [1].

High impact information on dld

A series of N-alkylmaleimides varying in chain length from N-ethyl up to and including N-heptyl, was shown to effectively inactivate Haemophilus influenzae D-lactate dehydrogenase at pH 7.0 and 25 degrees C in processes proposed to involve covalent modification of cysteine residues [2].

References

Purification and characterization of Haemophilus influenzae D-lactate dehydrogenase. Denicola-Seoane, A., Anderson, B.M. J. Biol. Chem. (1990) [Pubmed]
Nonpolar interactions in the maleimide inactivation of Haemophilus influenzae D-lactate dehydrogenase. Denicola-Seoane, A., Anderson, B.M. Biochim. Biophys. Acta (1990) [Pubmed]

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