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MeSH Review

Haemophilus

 
 
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Disease relevance of Haemophilus

 

Psychiatry related information on Haemophilus

  • We investigated the relationship between the form of the Haemophilus influenzae type B (Hib) polysaccharide (PS)-protein conjugate vaccine, Id expression, and Ab quality [6].
 

High impact information on Haemophilus

 

Chemical compound and disease context of Haemophilus

 

Biological context of Haemophilus

 

Anatomical context of Haemophilus

  • OBJECTIVES: To compare IgA1 protease activity in nontypeable H influenzae strains isolated from patients with symptomatic Haemophilus infection (sputum, cerebrospinal fluid, blood, or normally sterile tissue) vs strains from throat swabs of asymptomatic carriers and to compare iga gene carriage and variability in nontypeable H influenzae strains [7].
  • Treatment with L-659,989 decreased abnormal cerebrospinal fluid cytochemical values induced by intracisternal challenge with pneumococci but not Haemophilus influenzae, indicating a special role for PAF in pneumococcal disease [20].
  • The capsular polysaccharide of Hemophilus influenzae type b, polyribosyl ribitol phosphate (PRP), is released from growing organisms during human infection and can be found in body fluids [21].
  • Human milk lactoferrin inactivates two putative colonization factors expressed by Haemophilus influenzae [22].
  • In vitro production of human antibody to the Haemophilus influenzae type b capsular polysaccharide (PRP) and to tetanus toxoid (TT) and diphtheria toxoid was measured in culture supernatants of peripheral blood mononuclear cells and by enumeration of antibody secreting cells (AbSC) in an enzyme-linked immunosorbent-plaquing assay [23].
 

Gene context of Haemophilus

  • Inhibition of p38 MAPK by glucocorticoids via induction of MAPK phosphatase-1 enhances nontypeable Haemophilus influenzae-induced expression of toll-like receptor 2 [24].
  • Glucocorticoids synergistically enhance nontypeable Haemophilus influenzae-induced Toll-like receptor 2 expression via a negative cross-talk with p38 MAP kinase [25].
  • Transforming growth factor-beta -Smad signaling pathway cooperates with NF-kappa B to mediate nontypeable Haemophilus influenzae-induced MUC2 mucin transcription [26].
  • Mutation of the htrB locus of Haemophilus influenzae nontypable strain 2019 is associated with modifications of lipid A and phosphorylation of the lipo-oligosaccharide [27].
  • Novel cytoplasmic proteins of nontypeable Haemophilus influenzae up-regulate human MUC5AC mucin transcription via a positive p38 mitogen-activated protein kinase pathway and a negative phosphoinositide 3-kinase-Akt pathway [28].
 

Analytical, diagnostic and therapeutic context of Haemophilus

References

  1. The efficacy in Navajo infants of a conjugate vaccine consisting of Haemophilus influenzae type b polysaccharide and Neisseria meningitidis outer-membrane protein complex. Santosham, M., Wolff, M., Reid, R., Hohenboken, M., Bateman, M., Goepp, J., Cortese, M., Sack, D., Hill, J., Newcomer, W. N. Engl. J. Med. (1991) [Pubmed]
  2. Nonspecific vaginitis: role of Haemophilus vaginalis and treatment with metronidazole. Pheifer, T.A., Forsyth, P.S., Durfee, M.A., Pollock, H.M., Holmes, K.K. N. Engl. J. Med. (1978) [Pubmed]
  3. Streptomycin and sulfisoxazole for treatment of Haemophilus influenzae meningitis. Meade, R.H. JAMA (1978) [Pubmed]
  4. The treatment of chancroid. Schmid, G.P. JAMA (1986) [Pubmed]
  5. Purification and characterization of Haemophilus influenzae pili, and their structural and serological relatedness to Escherichia coli P and mannose-sensitive pili. Guerina, N.G., Langermann, S., Schoolnik, G.K., Kessler, T.W., Goldmann, D.A. J. Exp. Med. (1985) [Pubmed]
  6. Functional differences in idiotypically defined IgG1 anti-polysaccharide antibodies elicited by vaccination with Haemophilus influenzae type B polysaccharide-protein conjugates. Lucas, A.H., Granoff, D.M. J. Immunol. (1995) [Pubmed]
  7. Nontypeable Haemophilus influenzae in carriage and disease: a difference in IgA1 protease activity levels. Vitovski, S., Dunkin, K.T., Howard, A.J., Sayers, J.R. JAMA (2002) [Pubmed]
  8. The Haemophilus influenzae Hap serine protease promotes adherence and microcolony formation, potentiated by a soluble host protein. Hendrixson, D.R., St Geme, J.W. Mol. Cell (1998) [Pubmed]
  9. Phosphorylcholine on the lipopolysaccharide of Haemophilus influenzae contributes to persistence in the respiratory tract and sensitivity to serum killing mediated by C-reactive protein. Weiser, J.N., Pan, N., McGowan, K.L., Musher, D., Martin, A., Richards, J. J. Exp. Med. (1998) [Pubmed]
  10. Efficacy of Haemophilus influenzae type b polysaccharide-diphtheria toxoid conjugate vaccine in infancy. Eskola, J., Peltola, H., Takala, A.K., Käyhty, H., Hakulinen, M., Karanko, V., Kela, E., Rekola, P., Rönnberg, P.R., Samuelson, J.S. N. Engl. J. Med. (1987) [Pubmed]
  11. The increasing incidence of Ampicillin-resistant Haemophilus influenzae. A cause of otitis media. Schwartz, R., Rodriguez, W., Khan, W., Ross, S. JAMA (1978) [Pubmed]
  12. Elaboration of type b capsule by Haemophilus influenzae as a determinant of pathogenicity and impaired killing by trimethoprim-sulfamethoxazole. Yogev, R., Moxon, E.R. J. Clin. Invest. (1982) [Pubmed]
  13. Circulating polyribophosphate in Hemophilus influenzae, type b meningitis. Correlation with clinical course and antibody response. O'Reilly, R.J., Anderson, P., Ingram, D.L., Peter, G., Smith, D.H. J. Clin. Invest. (1975) [Pubmed]
  14. Role of complement in mouse macrophage binding of Haemophilus influenzae type b. Noel, G.J., Mosser, D.M., Edelson, P.J. J. Clin. Invest. (1990) [Pubmed]
  15. Impaired antibody response to Haemophilus influenzae type b polysaccharide and low IgG2 and IgG4 concentrations in Apache children. Siber, G.R., Santosham, M., Reid, G.R., Thompson, C., Almeido-Hill, J., Morell, A., deLange, G., Ketcham, J.K., Callahan, E.H. N. Engl. J. Med. (1990) [Pubmed]
  16. DNA repeats identify novel virulence genes in Haemophilus influenzae. Hood, D.W., Deadman, M.E., Jennings, M.P., Bisercic, M., Fleischmann, R.D., Venter, J.C., Moxon, E.R. Proc. Natl. Acad. Sci. U.S.A. (1996) [Pubmed]
  17. Nephrotic syndrome with crescent formation and massive IgA deposition following allogeneic bone marrow transplantation for natural killer cell leukemia/lymphoma. Kimura, S., Horie, A., Hiki, Y., Yamamoto, C., Suzuki, S., Kuroda, J., Deguchi, M., Kato, G., Karasuno, T., Hiraoka, A., Yoshikawa, T., Maekawa, T. Blood (2003) [Pubmed]
  18. Gene expression changes triggered by exposure of Haemophilus influenzae to novobiocin or ciprofloxacin: combined transcription and translation analysis. Gmuender, H., Kuratli, K., Di Padova K, n.u.l.l., Gray, C.P., Keck, W., Evers, S. Genome Res. (2001) [Pubmed]
  19. Biochemical characterization of a Haemophilus influenzae periplasmic iron transport operon. Adhikari, P., Kirby, S.D., Nowalk, A.J., Veraldi, K.L., Schryvers, A.B., Mietzner, T.A. J. Biol. Chem. (1995) [Pubmed]
  20. Differing roles for platelet-activating factor during inflammation of the lung and subarachnoid space. The special case of Streptococcus pneumoniae. Cabellos, C., MacIntyre, D.E., Forrest, M., Burroughs, M., Prasad, S., Tuomanen, E. J. Clin. Invest. (1992) [Pubmed]
  21. Pathophysiology of hemolysis in infections with Hemophilus influenzae type b. Shurin, S.B., Anderson, P., Zollinger, J., Rathbun, R.K. J. Clin. Invest. (1986) [Pubmed]
  22. Human milk lactoferrin inactivates two putative colonization factors expressed by Haemophilus influenzae. Qiu, J., Hendrixson, D.R., Baker, E.N., Murphy, T.F., St Geme, J.W., Plaut, A.G. Proc. Natl. Acad. Sci. U.S.A. (1998) [Pubmed]
  23. In vitro human antibody production to the Haemophilus influenzae type b capsular polysaccharide. Munoz, J.L., Insel, R.A. J. Immunol. (1987) [Pubmed]
  24. Inhibition of p38 MAPK by glucocorticoids via induction of MAPK phosphatase-1 enhances nontypeable Haemophilus influenzae-induced expression of toll-like receptor 2. Imasato, A., Desbois-Mouthon, C., Han, J., Kai, H., Cato, A.C., Akira, S., Li, J.D. J. Biol. Chem. (2002) [Pubmed]
  25. Glucocorticoids synergistically enhance nontypeable Haemophilus influenzae-induced Toll-like receptor 2 expression via a negative cross-talk with p38 MAP kinase. Shuto, T., Imasato, A., Jono, H., Sakai, A., Xu, H., Watanabe, T., Rixter, D.D., Kai, H., Andalibi, A., Linthicum, F., Guan, Y.L., Han, J., Cato, A.C., Lim, D.J., Akira, S., Li, J.D. J. Biol. Chem. (2002) [Pubmed]
  26. Transforming growth factor-beta -Smad signaling pathway cooperates with NF-kappa B to mediate nontypeable Haemophilus influenzae-induced MUC2 mucin transcription. Jono, H., Shuto, T., Xu, H., Kai, H., Lim, D.J., Gum, J.R., Kim, Y.S., Yamaoka, S., Feng, X.H., Li, J.D. J. Biol. Chem. (2002) [Pubmed]
  27. Mutation of the htrB locus of Haemophilus influenzae nontypable strain 2019 is associated with modifications of lipid A and phosphorylation of the lipo-oligosaccharide. Lee, N.G., Sunshine, M.G., Engstrom, J.J., Gibson, B.W., Apicella, M.A. J. Biol. Chem. (1995) [Pubmed]
  28. Novel cytoplasmic proteins of nontypeable Haemophilus influenzae up-regulate human MUC5AC mucin transcription via a positive p38 mitogen-activated protein kinase pathway and a negative phosphoinositide 3-kinase-Akt pathway. Wang, B., Lim, D.J., Han, J., Kim, Y.S., Basbaum, C.B., Li, J.D. J. Biol. Chem. (2002) [Pubmed]
  29. Hemophilus influenzae type B disease in children vaccinated with type B polysaccharide vaccine. Granoff, D.M., Shackelford, P.G., Suarez, B.K., Nahm, M.H., Cates, K.L., Murphy, T.V., Karasic, R., Osterholm, M.T., Pandey, J.P., Daum, R.S. N. Engl. J. Med. (1986) [Pubmed]
  30. The protective efficacy of Haemophilus b polysaccharide vaccine. Shapiro, E.D., Murphy, T.V., Wald, E.R., Brady, C.A. JAMA (1988) [Pubmed]
  31. Ampicillin treatment failure of apparently beta-lactamase-negative Haemophilus influenzae type b meningitis due to novel beta-lactamase. Rubin, L.G., Medeiros, A.A., Yolken, R.H., Moxon, E.R. Lancet (1981) [Pubmed]
  32. Immunogenicity of a Haemophilus influenzae polysaccharide-Neisseria meningitidis outer membrane protein complex conjugate vaccine. Donnelly, J.J., Deck, R.R., Liu, M.A. J. Immunol. (1990) [Pubmed]
  33. Intrinsic tritium labeling of the capsular polysaccharide antigen of Haemophilus influenzae type B. Anderson, P. J. Immunol. (1978) [Pubmed]
 
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