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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

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Gene Review: 

CalHV3gp19  -  ORF16

Callitrichine herpesvirus 3

 
 
 
 
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Disease relevance of CalHV3gp19

  • Furthermore, the herpesvirus Bcl-2 homologs including KSbcl-2, BHRF1, and ORF16 of herpesvirus saimiri contain poorly conserved Bcl-2 homology 3 (BH3) domains compared with other mammalian Bcl-2 homologs, implying that BH3 may not be essential for anti-apoptotic function [1].

References

  1. A Bcl-2 homolog encoded by Kaposi sarcoma-associated virus, human herpesvirus 8, inhibits apoptosis but does not heterodimerize with Bax or Bak. Cheng, E.H., Nicholas, J., Bellows, D.S., Hayward, G.S., Guo, H.G., Reitz, M.S., Hardwick, J.M. Proc. Natl. Acad. Sci. U.S.A. (1997) [Pubmed]
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