Gene Review:
BHRF1 - BHRF1
Human herpesvirus 4
- Long-term MHC class II presentation of the EBV lytic protein BHRF1 by EBV latently infected b cells following capture of BHRF1 antigen. Landais, E., Saulquin, X., Bonneville, M., Houssaint, E. J. Immunol. (2005)
- Isolation and characterization of cDNA clones corresponding to transcripts from the BamHI H and F regions of the Epstein-Barr virus genome. Pfitzner, A.J., Tsai, E.C., Strominger, J.L., Speck, S.H. J. Virol. (1987)
- Identification of an Epstein-Barr virus early gene encoding a second component of the restricted early antigen complex. Pearson, G.R., Luka, J., Petti, L., Sample, J., Birkenbach, M., Braun, D., Kieff, E. Virology (1987)
- Mitochondria as functional targets of proteins coded by human tumor viruses. D'Agostino, D.M., Bernardi, P., Chieco-Bianchi, L., Ciminale, V. Adv. Cancer Res. (2005)
- Complex transcription of the Epstein-Barr virus BamHI fragment H rightward open reading frame 1 (BHRF1) in latently and lytically infected B lymphocytes. Austin, P.J., Flemington, E., Yandava, C.N., Strominger, J.L., Speck, S.H. Proc. Natl. Acad. Sci. U.S.A. (1988)
- Viral modulators of cell death provide new links to old pathways. Irusta, P.M., Chen, Y.B., Hardwick, J.M. Curr. Opin. Cell Biol. (2003)
- A Bcl-2 homolog encoded by Kaposi sarcoma-associated virus, human herpesvirus 8, inhibits apoptosis but does not heterodimerize with Bax or Bak. Cheng, E.H., Nicholas, J., Bellows, D.S., Hayward, G.S., Guo, H.G., Reitz, M.S., Hardwick, J.M. Proc. Natl. Acad. Sci. U.S.A. (1997)
- Epstein-Barr virus-coded BHRF1 protein, a viral homologue of Bcl-2, protects human B cells from programmed cell death. Henderson, S., Huen, D., Rowe, M., Dawson, C., Johnson, G., Rickinson, A. Proc. Natl. Acad. Sci. U.S.A. (1993)
- BHRF1, a viral homologue of the Bcl-2 oncogene, is conserved at both the sequence and functional level in different Epstein-Barr virus isolates. Khanim, F., Dawson, C., Meseda, C.A., Dawson, J., Mackett, M., Young, L.S. J. Gen. Virol. (1997)
- BHRF1, the Epstein-Barr virus (EBV) homologue of the BCL-2 protooncogene, is transcribed in EBV-associated B-cell lymphomas and in reactive lymphocytes. Oudejans, J.J., van den Brule, A.J., Jiwa, N.M., de Bruin, P.C., Ossenkoppele, G.J., van der Valk, P., Walboomers, J.M., Meijer, C.J. Blood (1995)
- Ultrastructural localization of BHRF1: an Epstein-Barr virus gene product which has homology with bcl-2. Hickish, T., Robertson, D., Clarke, P., Hill, M., di Stefano, F., Clarke, C., Cunningham, D. Cancer Res. (1994)
- The cellular protein PRA1 modulates the anti-apoptotic activity of Epstein-Barr virus BHRF1, a homologue of Bcl-2, through direct interaction. Li, L.Y., Shih, H.M., Liu, M.Y., Chen, J.Y. J. Biol. Chem. (2001)
- BHRF1, a viral homologue of the Bcl-2 oncogene, disturbs epithelial cell differentiation. Dawson, C.W., Eliopoulos, A.G., Dawson, J., Young, L.S. Oncogene (1995)
- The ability of BHRF1 to inhibit apoptosis is dependent on stimulus and cell type. Foghsgaard, L., Jäättelä, M. J. Virol. (1997)
- Epstein-Barr virus BHRF1 protein protects intestine 407 epithelial cells from apoptosis induced by tumor necrosis factor alpha and anti-Fas antibody. Kawanishi, M. J. Virol. (1997)
- Epstein-Barr virus BHRF1 protein protects against cell death induced by DNA-damaging agents and heterologous viral infection. Tarodi, B., Subramanian, T., Chinnadurai, G. Virology (1994)
- Epstein-Barr virus (EBV) nuclear antigen leader protein (EBNA-LP) forms complexes with a cellular anti-apoptosis protein Bcl-2 or its EBV counterpart BHRF1 through HS1-associated protein X-1. Matsuda, G., Nakajima, K., Kawaguchi, Y., Yamanashi, Y., Hirai, K. Microbiol. Immunol. (2003)
- Reactivation of the Epstein-Barr virus from viral latency by an S-adenosylhomocysteine hydrolase/14-3-3 zeta/PLA2-dependent pathway. Maas, D., Maret, C., Schaade, L., Scheithauer, S., Ritter, K., Kleines, M. Med. Microbiol. Immunol. (Berl.) (2006)
- Expression of proteins encoded by Epstein-Barr virus trans-activator genes depends on the differentiation of epithelial cells in oral hairy leukoplakia. Becker, J., Leser, U., Marschall, M., Langford, A., Jilg, W., Gelderblom, H., Reichart, P., Wolf, H. Proc. Natl. Acad. Sci. U.S.A. (1991)
- Role of the epstein-barr virus RTA protein in activation of distinct classes of viral lytic cycle genes. Ragoczy, T., Miller, G. J. Virol. (1999)
- Epstein-Barr virus BALF1 is a BCL-2-like antagonist of the herpesvirus antiapoptotic BCL-2 proteins. Bellows, D.S., Howell, M., Pearson, C., Hazlewood, S.A., Hardwick, J.M. J. Virol. (2002)
- The latency pattern of Epstein-Barr virus infection and viral IL-10 expression in cutaneous natural killer/T-cell lymphomas. Xu, Z.G., Iwatsuki, K., Oyama, N., Ohtsuka, M., Satoh, M., Kikuchi, S., Akiba, H., Kaneko, F. Br. J. Cancer (2001)