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Gene Review:

rnc - ribonuclease III

Escherichia coli O157:H7 str. EDL933

Verma, A. et al., Pertzev, A.V. et al.

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Disease relevance of rncS

The precursor transcripts are processed into mature 16S rRNA through a pathway that includes recognition of RNA secondary structure by ribonuclease III (RNase III) in the stem structure surrounding the 16S rRNA indicating that at least this RNA processing step is conserved in mycobacteria and E. coli [1].

High impact information on rncS

Characterization of RNA sequence determinants and antideterminants of processing reactivity for a minimal substrate of Escherichia coli ribonuclease III [2].
Members of the ribonuclease III family are the primary agents of double-stranded (ds) RNA processing in prokaryotic and eukaryotic cells [2].

References

Functional analysis of transcription of the Mycobacterium tuberculosis 16S rDNA-encoding gene. Verma, A., Kinger, A.K., Tyagi, J.S. Gene (1994) [Pubmed]
Characterization of RNA sequence determinants and antideterminants of processing reactivity for a minimal substrate of Escherichia coli ribonuclease III. Pertzev, A.V., Nicholson, A.W. Nucleic Acids Res. (2006) [Pubmed]

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