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Gene Review

Z1640  -  hypothetical protein

Escherichia coli O157:H7 str. EDL933

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Disease relevance of Z1640

  • In a PCR investigation of 36 VTEC strains of different serotypes, intact Z1640 was present in strains of serotypes O157:H7, O26:H11, O103:H2, O111:NM, and O145:NM, which are associated with hemolytic uremic syndrome and outbreaks [1].

High impact information on Z1640

  • In contrast, fragmented Z1640 was seen in strains of nonepidemic serotypes, such as O91:H21 and O113:H21, and in animal serotypes that have not been associated with human disease, indicating that Z1640 might be a virulence gene [1].


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