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Gene Review:

RUSC2 - RUN and SH3 domain containing 2

Homo sapiens

Synonyms: Interacting protein of Rab1, Iporin, KIAA0375, RUN and SH3 domain-containing protein 2

Katoh, M. et al., Bayer, M. et al.

Bayer, Fischer, Kremerskothen, Ossendorf, Matanis, Konczal, Weide, Barnekow, Katoh, Katoh,

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High impact information on RUSC2

RUSC1 isoform 1 (1039 aa) and RUSC2 (1516 aa) showed 30.5% total amino-acid identity [1].
RUSC2 gene, consisting of 12 exons was mapped to human chromosome 9p13 [1].
RESULTS: Here, we report the characterization of Iporin, which is similar to KIAA0375 as a novel rab1-interacting protein [2].

Biological context of RUSC2

Here, we characterized RUSC1 and RUSC2 genes by using bioinformatics [1].

References

Characterization of RUSC1 and RUSC2 genes in silico. Katoh, M., Katoh, M. Oncol. Rep. (2004) [Pubmed]
Identification and characterization of Iporin as a novel interaction partner for rab1. Bayer, M., Fischer, J., Kremerskothen, J., Ossendorf, E., Matanis, T., Konczal, M., Weide, T., Barnekow, A. BMC Cell Biol. (2005) [Pubmed]

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